LINC01615

Summary

LINC01615 (long intergenic non-protein coding RNA 1615, HGNC:51898) is a long non-coding RNA gene on chromosome 6q27.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51898
Approved symbol	LINC01615
Name	long intergenic non-protein coding RNA 1615
Location	6q27
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-417E7.1
Ensembl gene	ENSG00000223485
Ensembl biotype	lncRNA
Entrez	101929484
RNAcentral	URS00008E394F — lncRNA, 772 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 26 — 26 lncRNA

ENST00000439703, ENST00000449466, ENST00000564830, ENST00000634877, ENST00000651190, ENST00000657431, ENST00000715775, ENST00000831997, ENST00000831998, ENST00000831999, ENST00000832000, ENST00000832001, ENST00000832002, ENST00000832003, ENST00000832004, ENST00000832005, ENST00000832006, ENST00000832007, ENST00000832008, ENST00000832009, ENST00000832010, ENST00000832011, ENST00000832012, ENST00000832013, ENST00000832014, ENST00000832015

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000439703 — 2 exons

Exon	Start	End
ENSE00001599879	169158092	169158456
ENSE00001697280	169162643	169162924

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 96.80.

FANTOM5 (CAGE): breadth broad, TPM avg 3.3448 / max 437.0994, expressed in 489 samples.

FANTOM5 promoters (9 alternative TSS)

Promoter ID	TPM avg	Samples expressed
76746	1.0803	195
76748	0.9030	207
76749	0.4587	140
76750	0.4539	216
76747	0.2069	101
76751	0.1810	111
76745	0.0473	19
76752	0.0338	11
76744	0.0136	6

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	96.80	gold quality
right coronary artery	UBERON:0001625	93.07	gold quality
left coronary artery	UBERON:0001626	87.28	gold quality
thoracic aorta	UBERON:0001515	80.77	gold quality
ascending aorta	UBERON:0001496	80.76	gold quality
descending thoracic aorta	UBERON:0002345	78.30	gold quality
tibial artery	UBERON:0007610	74.27	gold quality
popliteal artery	UBERON:0002250	74.24	gold quality
tibial nerve	UBERON:0001323	68.60	gold quality
skin of abdomen	UBERON:0001416	65.81	gold quality
zone of skin	UBERON:0000014	64.55	gold quality
stromal cell of endometrium	CL:0002255	64.33	gold quality
skin of leg	UBERON:0001511	63.87	gold quality
endocervix	UBERON:0000458	62.93	gold quality
ectocervix	UBERON:0012249	61.60	gold quality
hindlimb stylopod muscle	UBERON:0004252	60.72	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	60.18	gold quality
urinary bladder	UBERON:0001255	60.10	gold quality
heart	UBERON:0000948	59.37	gold quality
subcutaneous adipose tissue	UBERON:0002190	58.87	gold quality
endometrium	UBERON:0001295	58.06	gold quality
placenta	UBERON:0001987	57.44	gold quality
gall bladder	UBERON:0002110	57.12	gold quality
right atrium auricular region	UBERON:0006631	57.05	gold quality
vagina	UBERON:0000996	56.03	gold quality
left adrenal gland cortex	UBERON:0035825	56.02	gold quality
islet of Langerhans	UBERON:0000006	55.95	gold quality
prefrontal cortex	UBERON:0000451	55.80	gold quality
multicellular organism	UBERON:0000468	55.62	gold quality
adipose tissue	UBERON:0001013	55.30	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.92

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 3)

• LINC01615 had 72 coexpressed genes, and we carried out the gene ontology (GO) term enrichment for these protein-coding genes (PMID:30556902)
• LINC01615 activates ZEB2 through competitively binding with miR-3653-3p to promote the carcinogenesis of colon cancer cells. (PMID:34965191)
• The Identification and Function of Linc01615 on Influenza Virus Infection and Antiviral Response. (PMID:38928290)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.