LINC01617

Summary

LINC01617 (long intergenic non-protein coding RNA 1617, HGNC:30442) is a long non-coding RNA gene on chromosome 8q21.11.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:30442
Approved symbol	LINC01617
Name	long intergenic non-protein coding RNA 1617
Location	8q21.11
Locus type	RNA, long non-coding
Status	Approved
Aliases	XLOC_006844
Entrez	101926947
RNAcentral	URS0000BC43D4 — lncRNA, 2597 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Authors found that LINC01617 was overexpressed in esophageal cancer, and its expression was associated with poor prognosis of esophageal cancer. In vitro experiments confirmed that knockout of LINC01617 significantly inhibited the proliferation, migration and invasion of esophageal cancer cells. (PMID:30120975)

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000331009 (8:73883297 T>A,C), RS1000406820 (8:73876989 G>A), RS1000465291 (8:73882828 T>C), RS1000911121 (8:73878126 C>A), RS1000983917 (8:73882934 A>G), RS1001745358 (8:73881837 T>C), RS1002007722 (8:73882244 A>G), RS1002401206 (8:73878300 G>A), RS1002607583 (8:73880808 G>C), RS1002777988 (8:73878168 C>A,G), RS1002987679 (8:73879903 G>A), RS1003026599 (8:73880290 G>A), RS1003810021 (8:73879038 T>C,G), RS1004362123 (8:73878001 A>C), RS1004475413 (8:73878569 T>C)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.