LINC01621

Summary

LINC01621 (long intergenic non-protein coding RNA 1621, HGNC:14109) is a long non-coding RNA gene on chromosome 6q14.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:14109
Approved symbol	LINC01621
Name	long intergenic non-protein coding RNA 1621
Location	6q14.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235357
Ensembl biotype	lncRNA
Entrez	89758
RNAcentral	URS00008E3A26 — lncRNA, 748 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 24 — 24 lncRNA

ENST00000438797, ENST00000669965, ENST00000693479, ENST00000784459, ENST00000784460, ENST00000784461, ENST00000784462, ENST00000784463, ENST00000784464, ENST00000784465, ENST00000784466, ENST00000784467, ENST00000784468, ENST00000784469, ENST00000784470, ENST00000784471, ENST00000784472, ENST00000784473, ENST00000784474, ENST00000784475, ENST00000784476, ENST00000784477, ENST00000784478, ENST00000784479

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000438797 — 4 exons

Exon	Start	End
ENSE00001731090	79805896	79806048
ENSE00003880440	79807214	79807341
ENSE00003984612	79833155	79833387
ENSE00003984613	79803574	79803898

Expression profiles

Bgee: expression breadth broad, 81 present calls, max score 84.40.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0406 / max 31.9469, expressed in 9 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
74516	0.0406	9

Top tissues by expression

81 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.40	gold quality
nucleus accumbens	UBERON:0001882	69.74	gold quality
right lobe of liver	UBERON:0001114	68.71	gold quality
putamen	UBERON:0001874	68.34	gold quality
liver	UBERON:0002107	66.41	gold quality
caudate nucleus	UBERON:0001873	65.94	gold quality
cortical plate	UBERON:0005343	63.57	gold quality
ganglionic eminence	UBERON:0004023	63.17	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	61.01	gold quality
lower esophagus mucosa	UBERON:0035834	59.29	gold quality
skin of leg	UBERON:0001511	57.20	gold quality
zone of skin	UBERON:0000014	57.12	gold quality
primary visual cortex	UBERON:0002436	57.06	gold quality
skin of abdomen	UBERON:0001416	56.96	gold quality
hindlimb stylopod muscle	UBERON:0004252	56.08	silver quality
amygdala	UBERON:0001876	54.79	gold quality
monocyte	CL:0000576	54.59	gold quality
brain	UBERON:0000955	53.98	gold quality
substantia nigra	UBERON:0002038	53.37	gold quality
prefrontal cortex	UBERON:0000451	53.22	gold quality
multicellular organism	UBERON:0000468	52.42	gold quality
blood	UBERON:0000178	51.89	gold quality
heart	UBERON:0000948	51.69	gold quality
esophagus mucosa	UBERON:0002469	50.13	gold quality
esophagus	UBERON:0001043	50.03	gold quality
islet of Langerhans	UBERON:0000006	49.87	gold quality
placenta	UBERON:0001987	49.81	gold quality
cortex of kidney	UBERON:0001225	49.73	gold quality
hypothalamus	UBERON:0001898	49.68	gold quality
cerebellum	UBERON:0002037	49.52	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.