LINC01630

Summary

LINC01630 (long intergenic non-protein coding RNA 1630, HGNC:52295) is a long non-coding RNA gene on chromosome 18q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52295
Approved symbol	LINC01630
Name	long intergenic non-protein coding RNA 1630
Location	18q21.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	LOC100287225
Ensembl gene	ENSG00000227115
Ensembl biotype	lncRNA
Entrez	100287225
RNAcentral	URS000046ECC3 — lncRNA, 1799 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 31 — 31 lncRNA

ENST00000435144, ENST00000578152, ENST00000580841, ENST00000582689, ENST00000583609, ENST00000635103, ENST00000635503, ENST00000635680, ENST00000655280, ENST00000658078, ENST00000659333, ENST00000659439, ENST00000660545, ENST00000661773, ENST00000662191, ENST00000662744, ENST00000665420, ENST00000665482, ENST00000666929, ENST00000666962, ENST00000686712, ENST00000845487, ENST00000845488, ENST00000845489, ENST00000845490, ENST00000845491, ENST00000845492, ENST00000845493, ENST00000845494, ENST00000845495, ENST00000845496

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000435144 — 7 exons

Exon	Start	End
ENSE00001649111	51561181	51564479
ENSE00001785134	51560593	51560886
ENSE00003787643	51578406	51578676
ENSE00003789236	51633449	51633546
ENSE00003790377	51582322	51582438
ENSE00003790428	51634880	51636073
ENSE00003861414	51392039	51392257

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 90.43.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.6458 / max 95.6923, expressed in 102 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
170273	0.3642	77
170276	0.1205	59
170274	0.1175	54
170275	0.0436	28

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
corpus callosum	UBERON:0002336	90.43	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	88.77	gold quality
substantia nigra	UBERON:0002038	86.02	gold quality
Ammon’s horn	UBERON:0001954	81.65	gold quality
putamen	UBERON:0001874	80.85	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.37	gold quality
amygdala	UBERON:0001876	80.14	gold quality
temporal lobe	UBERON:0001871	79.92	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.04	gold quality
hypothalamus	UBERON:0001898	76.58	gold quality
primary visual cortex	UBERON:0002436	73.51	gold quality
caudate nucleus	UBERON:0001873	73.04	gold quality
prefrontal cortex	UBERON:0000451	72.43	gold quality
cerebral cortex	UBERON:0000956	72.42	gold quality
Brodmann (1909) area 9	UBERON:0013540	72.08	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	71.40	gold quality
frontal cortex	UBERON:0001870	71.22	gold quality
colonic epithelium	UBERON:0000397	70.83	silver quality
brain	UBERON:0000955	70.65	gold quality
nucleus accumbens	UBERON:0001882	70.36	gold quality
bone marrow cell	CL:0002092	69.50	silver quality
right frontal lobe	UBERON:0002810	69.32	gold quality
anterior cingulate cortex	UBERON:0009835	68.50	gold quality
superior frontal gyrus	UBERON:0002661	68.26	gold quality
bone marrow	UBERON:0002371	64.04	gold quality
muscle tissue	UBERON:0002385	63.67	gold quality
ventricular zone	UBERON:0003053	63.58	gold quality
ganglionic eminence	UBERON:0004023	62.20	gold quality
skeletal muscle tissue	UBERON:0001134	61.89	gold quality
testis	UBERON:0000473	61.02	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.81

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.