LINC01637

Summary

LINC01637 (long intergenic non-protein coding RNA 1637, HGNC:52424) is a long non-coding RNA gene on chromosome 22q11.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52424
Approved symbol	LINC01637
Name	long intergenic non-protein coding RNA 1637
Location	22q11.21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237476
Ensembl biotype	lncRNA
Entrez	101928891
RNAcentral	URS000075A891 — lncRNA, 685 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000444039, ENST00000766621

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000444039 — 2 exons

Exon	Start	End
ENSE00003984194	20964391	20964682
ENSE00003984195	20957092	20957486

Expression profiles

Bgee: expression breadth ubiquitous, 126 present calls, max score 83.04.

FANTOM5 (CAGE): breadth broad, TPM avg 0.8936 / max 26.9185, expressed in 377 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
191172	0.8074	330
191173	0.0862	28

Top tissues by expression

126 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
mucosa of transverse colon	UBERON:0004991	83.04	gold quality
monocyte	CL:0000576	79.86	gold quality
transverse colon	UBERON:0001157	79.56	gold quality
leukocyte	CL:0000738	79.25	gold quality
granulocyte	CL:0000094	76.36	gold quality
right hemisphere of cerebellum	UBERON:0014890	74.78	gold quality
cerebellum	UBERON:0002037	73.83	gold quality
cerebellar cortex	UBERON:0002129	73.81	gold quality
cerebellar hemisphere	UBERON:0002245	73.80	gold quality
primary visual cortex	UBERON:0002436	73.45	gold quality
duodenum	UBERON:0002114	72.50	gold quality
colon	UBERON:0001155	71.99	gold quality
intestine	UBERON:0000160	71.24	gold quality
bone marrow	UBERON:0002371	71.12	gold quality
bone marrow cell	CL:0002092	70.41	silver quality
prefrontal cortex	UBERON:0000451	70.31	gold quality
small intestine	UBERON:0002108	69.84	gold quality
Brodmann (1909) area 9	UBERON:0013540	69.81	gold quality
frontal cortex	UBERON:0001870	69.77	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	69.74	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	69.73	gold quality
small intestine Peyer’s patch	UBERON:0003454	69.49	gold quality
rectum	UBERON:0001052	69.38	gold quality
right frontal lobe	UBERON:0002810	69.27	gold quality
pituitary gland	UBERON:0000007	68.80	gold quality
colonic epithelium	UBERON:0000397	68.24	silver quality
cerebral cortex	UBERON:0000956	68.07	gold quality
adenohypophysis	UBERON:0002196	67.74	gold quality
superior frontal gyrus	UBERON:0002661	67.52	gold quality
anterior cingulate cortex	UBERON:0009835	66.98	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.