LINC01643

Summary

LINC01643 (long intergenic non-protein coding RNA 1643, HGNC:52430) is a long non-coding RNA gene on chromosome 22q12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52430
Approved symbol	LINC01643
Name	long intergenic non-protein coding RNA 1643
Location	22q12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236052
Ensembl biotype	lncRNA
Entrez	105373010
RNAcentral	URS0000EEF1F5 — lncRNA, 1360 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 35 — 35 lncRNA

ENST00000412218, ENST00000652942, ENST00000653369, ENST00000654009, ENST00000655455, ENST00000655904, ENST00000656244, ENST00000656434, ENST00000657115, ENST00000658014, ENST00000658055, ENST00000658589, ENST00000658699, ENST00000659067, ENST00000661800, ENST00000661903, ENST00000663820, ENST00000664028, ENST00000664480, ENST00000664743, ENST00000665392, ENST00000665458, ENST00000665701, ENST00000667570, ENST00000668175, ENST00000668901, ENST00000669488, ENST00000669802, ENST00000670329, ENST00000670742, ENST00000671554, ENST00000803096, ENST00000803097, ENST00000803098, ENST00000803099

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412218 — 8 exons

Exon	Start	End
ENSE00001596320	34188330	34188425
ENSE00001612212	34151865	34151927
ENSE00001633781	34174310	34174447
ENSE00001717469	34100358	34100441
ENSE00001737804	34083969	34084027
ENSE00001750900	34017473	34017527
ENSE00001778393	34171713	34171778
ENSE00001783363	34161596	34161791

Expression profiles

Bgee: expression breadth broad, 57 present calls, max score 85.66.

Top tissues by expression

57 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.66	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	67.68	gold quality
right testis	UBERON:0004534	63.78	gold quality
sural nerve	UBERON:0015488	63.06	silver quality
superior frontal gyrus	UBERON:0002661	63.00	gold quality
testis	UBERON:0000473	62.84	gold quality
prefrontal cortex	UBERON:0000451	62.56	gold quality
left testis	UBERON:0004533	62.37	gold quality
frontal cortex	UBERON:0001870	57.88	gold quality
liver	UBERON:0002107	57.41	silver quality
Brodmann (1909) area 9	UBERON:0013540	55.79	gold quality
multicellular organism	UBERON:0000468	55.65	gold quality
cerebral cortex	UBERON:0000956	55.46	gold quality
brain	UBERON:0000955	54.75	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	54.70	gold quality
blood	UBERON:0000178	53.15	silver quality
monocyte	CL:0000576	52.79	gold quality
Ammon’s horn	UBERON:0001954	52.33	gold quality
primary visual cortex	UBERON:0002436	52.22	gold quality
muscle of leg	UBERON:0001383	51.81	gold quality
anterior cingulate cortex	UBERON:0009835	50.39	gold quality
gastrocnemius	UBERON:0001388	50.09	gold quality
right frontal lobe	UBERON:0002810	49.61	gold quality
substantia nigra	UBERON:0002038	49.35	gold quality
temporal lobe	UBERON:0001871	49.01	gold quality
amygdala	UBERON:0001876	48.71	gold quality
lower esophagus muscularis layer	UBERON:0035833	47.59	gold quality
caudate nucleus	UBERON:0001873	47.31	gold quality
putamen	UBERON:0001874	46.71	gold quality
corpus callosum	UBERON:0002336	45.67	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.76

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.