LINC01646

Summary

LINC01646 (long intergenic non-protein coding RNA 1646, HGNC:52433) is a long non-coding RNA gene on chromosome 1p36.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52433
Approved symbol	LINC01646
Name	long intergenic non-protein coding RNA 1646
Location	1p36.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000232596
Ensembl biotype	lncRNA
Entrez	105376679
RNAcentral	URS0000BC45E4 — lncRNA, 1028 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000420522, ENST00000634256, ENST00000635556, ENST00000659059, ENST00000659083, ENST00000661628, ENST00000666685, ENST00000667354

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000420522 — 5 exons

Exon	Start	End
ENSE00001622561	4583083	4583178
ENSE00001690743	4582277	4582574
ENSE00001696075	4571548	4571629
ENSE00001754951	4572470	4572592
ENSE00001801330	4583339	4583421

Expression profiles

Bgee: expression breadth broad, 43 present calls, max score 94.26.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0048 / max 4.0598, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
334	0.0048	3

Top tissues by expression

43 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	94.26	gold quality
urinary bladder	UBERON:0001255	75.99	silver quality
sural nerve	UBERON:0015488	69.08	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	65.54	gold quality
right testis	UBERON:0004534	60.43	gold quality
testis	UBERON:0000473	59.27	gold quality
left testis	UBERON:0004533	59.26	gold quality
multicellular organism	UBERON:0000468	54.91	gold quality
pancreas	UBERON:0001264	54.56	gold quality
blood	UBERON:0000178	54.15	gold quality
monocyte	CL:0000576	54.08	gold quality
prefrontal cortex	UBERON:0000451	53.37	gold quality
gall bladder	UBERON:0002110	50.59	gold quality
tibial nerve	UBERON:0001323	49.63	gold quality
frontal cortex	UBERON:0001870	48.12	gold quality
kidney	UBERON:0002113	46.23	silver quality
muscle of leg	UBERON:0001383	45.83	gold quality
thyroid gland	UBERON:0002046	44.97	gold quality
vermiform appendix	UBERON:0001154	44.87	silver quality
pituitary gland	UBERON:0000007	44.81	gold quality
left lobe of thyroid gland	UBERON:0001120	44.78	gold quality
adult mammalian kidney	UBERON:0000082	44.38	silver quality
lower esophagus muscularis layer	UBERON:0035833	44.27	gold quality
gastrocnemius	UBERON:0001388	42.87	gold quality
tonsil	UBERON:0002372	41.99	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	41.97	gold quality
putamen	UBERON:0001874	41.23	gold quality
body of stomach	UBERON:0001161	40.96	silver quality
right frontal lobe	UBERON:0002810	40.60	gold quality
body of pancreas	UBERON:0001150	40.57	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.79

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.