LINC01649

Summary

LINC01649 (long intergenic non-protein coding RNA 1649, HGNC:52436) is a long non-coding RNA gene on chromosome 1p13.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52436
Approved symbol	LINC01649
Name	long intergenic non-protein coding RNA 1649
Location	1p13.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228127
Ensembl biotype	lncRNA
Entrez	101928995
RNAcentral	URS00007E3F30 — lncRNA, 1411 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000438885, ENST00000634255, ENST00000659309, ENST00000659738, ENST00000665767, ENST00000669586, ENST00000671350, ENST00000784687

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000438885 — 3 exons

Exon	Start	End
ENSE00003790552	115922367	115922566
ENSE00003851257	115919376	115919559
ENSE00003879814	115924776	115926049

Expression profiles

Bgee: expression breadth broad, 92 present calls, max score 84.63.

Top tissues by expression

198 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.63	gold quality
right adrenal gland cortex	UBERON:0035827	71.45	gold quality
right adrenal gland	UBERON:0001233	70.54	gold quality
left adrenal gland	UBERON:0001234	67.87	gold quality
left adrenal gland cortex	UBERON:0035825	67.80	gold quality
adrenal cortex	UBERON:0001235	66.59	gold quality
adrenal gland	UBERON:0002369	65.98	gold quality
prefrontal cortex	UBERON:0000451	59.56	gold quality
cortical plate	UBERON:0005343	59.39	gold quality
buccal mucosa cell	CL:0002336	57.87	silver quality
adrenal tissue	UBERON:0018303	57.55	gold quality
Brodmann (1909) area 9	UBERON:0013540	57.10	gold quality
nucleus accumbens	UBERON:0001882	55.31	gold quality
hypothalamus	UBERON:0001898	55.23	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	54.82	gold quality
anterior cingulate cortex	UBERON:0009835	54.17	gold quality
cerebellar hemisphere	UBERON:0002245	54.15	gold quality
cerebellar cortex	UBERON:0002129	54.14	gold quality
frontal cortex	UBERON:0001870	53.77	gold quality
right hemisphere of cerebellum	UBERON:0014890	53.72	gold quality
neocortex	UBERON:0001950	53.59	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	53.52	gold quality
spinal cord	UBERON:0002240	53.45	gold quality
cerebellum	UBERON:0002037	53.17	gold quality
sperm	CL:0000019	53.06	silver quality
right frontal lobe	UBERON:0002810	52.73	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.00	gold quality
substantia nigra	UBERON:0002038	51.77	gold quality
cerebral cortex	UBERON:0000956	51.73	gold quality
left testis	UBERON:0004533	51.53	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.95

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.