LINC01659

Summary

LINC01659 (long intergenic non-protein coding RNA 1659, HGNC:52447) is a long non-coding RNA gene on chromosome 22q11.23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52447
Approved symbol	LINC01659
Name	long intergenic non-protein coding RNA 1659
Location	22q11.23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000234928
Ensembl biotype	lncRNA
Entrez	101929374
RNAcentral	URS00005847BA — lncRNA, 917 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 29 — 29 lncRNA

ENST00000428415, ENST00000449711, ENST00000454268, ENST00000457193, ENST00000684978, ENST00000786085, ENST00000786086, ENST00000786087, ENST00000786088, ENST00000786089, ENST00000786090, ENST00000786091, ENST00000786092, ENST00000786093, ENST00000786094, ENST00000786095, ENST00000786096, ENST00000786097, ENST00000786098, ENST00000786099, ENST00000786100, ENST00000786101, ENST00000786102, ENST00000786103, ENST00000786104, ENST00000786105, ENST00000786106, ENST00000786107, ENST00000786108

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000428415 — 3 exons

Exon	Start	End
ENSE00004162504	23460353	23461455
ENSE00004162510	23433542	23434335
ENSE00004162511	23434560	23435076

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 74.52.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0165 / max 3.3323, expressed in 7 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
209415	0.0165	7

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	74.52	gold quality
sural nerve	UBERON:0015488	74.14	gold quality
ventricular zone	UBERON:0003053	71.45	gold quality
left ovary	UBERON:0002119	71.06	gold quality
ovary	UBERON:0000992	69.91	gold quality
mucosa of transverse colon	UBERON:0004991	68.39	gold quality
right ovary	UBERON:0002118	66.86	gold quality
prostate gland	UBERON:0002367	66.77	gold quality
bone marrow cell	CL:0002092	66.50	silver quality
colonic epithelium	UBERON:0000397	66.31	silver quality
endometrium	UBERON:0001295	65.83	gold quality
rectum	UBERON:0001052	64.60	gold quality
body of pancreas	UBERON:0001150	64.22	gold quality
right lobe of liver	UBERON:0001114	64.07	gold quality
liver	UBERON:0002107	63.58	gold quality
ganglionic eminence	UBERON:0004023	63.39	gold quality
small intestine	UBERON:0002108	62.70	gold quality
small intestine Peyer’s patch	UBERON:0003454	62.69	gold quality
transverse colon	UBERON:0001157	62.24	gold quality
pancreas	UBERON:0001264	61.96	gold quality
monocyte	CL:0000576	61.34	gold quality
fallopian tube	UBERON:0003889	61.26	gold quality
urinary bladder	UBERON:0001255	60.64	gold quality
skin of leg	UBERON:0001511	60.24	gold quality
intestine	UBERON:0000160	60.02	gold quality
adult mammalian kidney	UBERON:0000082	59.97	gold quality
gall bladder	UBERON:0002110	59.95	gold quality
zone of skin	UBERON:0000014	59.76	gold quality
kidney	UBERON:0002113	59.60	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.56	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.