LINC01665

Summary

LINC01665 (long intergenic non-protein coding RNA 1665, HGNC:52453) is a long non-coding RNA gene on chromosome 22q11.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52453
Approved symbol	LINC01665
Name	long intergenic non-protein coding RNA 1665
Location	22q11.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235343
Ensembl biotype	lncRNA
Entrez	101929350
RNAcentral	URS00008C2A01 — lncRNA, 1049 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000422917, ENST00000665507, ENST00000839187, ENST00000839188, ENST00000839189

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000422917 — 2 exons

Exon	Start	End
ENSE00001677923	16746869	16747739
ENSE00001764059	16748276	16748645

Expression profiles

Bgee: expression breadth broad, 30 present calls, max score 86.61.

Top tissues by expression

30 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.61	gold quality
heart left ventricle	UBERON:0002084	53.48	gold quality
prefrontal cortex	UBERON:0000451	51.74	gold quality
testis	UBERON:0000473	51.70	gold quality
right testis	UBERON:0004534	51.61	gold quality
left testis	UBERON:0004533	51.56	gold quality
cortex of kidney	UBERON:0001225	51.03	gold quality
multicellular organism	UBERON:0000468	48.07	gold quality
stomach	UBERON:0000945	47.99	gold quality
blood	UBERON:0000178	47.89	silver quality
cerebral cortex	UBERON:0000956	47.80	gold quality
monocyte	CL:0000576	47.65	silver quality
gastrocnemius	UBERON:0001388	47.51	gold quality
Ammon’s horn	UBERON:0001954	47.49	gold quality
adult mammalian kidney	UBERON:0000082	45.88	gold quality
right atrium auricular region	UBERON:0006631	45.34	silver quality
body of stomach	UBERON:0001161	45.00	gold quality
minor salivary gland	UBERON:0001830	44.70	gold quality
islet of Langerhans	UBERON:0000006	43.53	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	42.95	silver quality
skin of leg	UBERON:0001511	39.86	silver quality
zone of skin	UBERON:0000014	39.83	silver quality
ascending aorta	UBERON:0001496	39.36	silver quality
skin of abdomen	UBERON:0001416	39.26	silver quality
right frontal lobe	UBERON:0002810	38.70	silver quality
hypothalamus	UBERON:0001898	38.38	silver quality
left lobe of thyroid gland	UBERON:0001120	37.74	silver quality
metanephros cortex	UBERON:0010533	36.65	silver quality
substantia nigra	UBERON:0002038	36.31	silver quality
subcutaneous adipose tissue	UBERON:0002190	35.73	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.15

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.