LINC01666

Summary

LINC01666 (long intergenic non-protein coding RNA 1666, HGNC:52454) is a long non-coding RNA gene on chromosome 21p11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52454
Approved symbol	LINC01666
Name	long intergenic non-protein coding RNA 1666
Location	21p11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000279579
Ensembl biotype	lncRNA
Entrez	105372730
RNAcentral	URS00026A2387 — lncRNA, 370 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 60 — 60 lncRNA

ENST00000623794, ENST00000624813, ENST00000815440, ENST00000815441, ENST00000815442, ENST00000815443, ENST00000815444, ENST00000815445, ENST00000815446, ENST00000815447, ENST00000815448, ENST00000815449, ENST00000815450, ENST00000815451, ENST00000815452, ENST00000815453, ENST00000815454, ENST00000815455, ENST00000815456, ENST00000815457, ENST00000815458, ENST00000815459, ENST00000815460, ENST00000815461, ENST00000815462, ENST00000815463, ENST00000815464, ENST00000815465, ENST00000815466, ENST00000815467, ENST00000815468, ENST00000815469, ENST00000815470, ENST00000815471, ENST00000815472, ENST00000815473, ENST00000815474, ENST00000815475, ENST00000815476, ENST00000815477, ENST00000815478, ENST00000815479, ENST00000815480, ENST00000815481, ENST00000815482, ENST00000815483, ENST00000815484, ENST00000815485, ENST00000815486, ENST00000815487, ENST00000815488, ENST00000815489, ENST00000815490, ENST00000815491, ENST00000815492, ENST00000815493, ENST00000815494, ENST00000815495, ENST00000815496, ENST00000815497

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000623794 — 2 exons

Exon	Start	End
ENSE00003755112	8761276	8761335
ENSE00003755809	8759077	8759861

Expression profiles

Bgee: expression breadth ubiquitous, 116 present calls, max score 81.87.

Top tissues by expression

116 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.87	gold quality
bone marrow cell	CL:0002092	81.16	gold quality
cortical plate	UBERON:0005343	77.54	gold quality
cortex of kidney	UBERON:0001225	76.35	gold quality
colonic epithelium	UBERON:0000397	74.33	silver quality
ganglionic eminence	UBERON:0004023	72.95	gold quality
bone marrow	UBERON:0002371	72.47	gold quality
skeletal muscle tissue	UBERON:0001134	69.04	gold quality
prefrontal cortex	UBERON:0000451	68.68	gold quality
sural nerve	UBERON:0015488	65.35	gold quality
liver	UBERON:0002107	64.83	gold quality
uterine cervix	UBERON:0000002	63.51	gold quality
tonsil	UBERON:0002372	62.87	gold quality
blood	UBERON:0000178	61.84	gold quality
superior frontal gyrus	UBERON:0002661	61.61	gold quality
ectocervix	UBERON:0012249	61.23	gold quality
smooth muscle tissue	UBERON:0001135	61.20	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	61.19	gold quality
right lung	UBERON:0002167	60.91	gold quality
endocervix	UBERON:0000458	60.66	gold quality
urinary bladder	UBERON:0001255	59.88	gold quality
kidney	UBERON:0002113	59.88	gold quality
muscle of leg	UBERON:0001383	59.38	gold quality
right adrenal gland cortex	UBERON:0035827	59.38	gold quality
right ovary	UBERON:0002118	59.34	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.14	gold quality
gastrocnemius	UBERON:0001388	59.00	gold quality
tibial artery	UBERON:0007610	58.86	gold quality
right lobe of liver	UBERON:0001114	58.74	gold quality
mucosa of stomach	UBERON:0001199	58.59	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.36

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.