LINC01671

Summary

LINC01671 (long intergenic non-protein coding RNA 1671, HGNC:52459) is a long non-coding RNA gene on chromosome 21q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52459
Approved symbol	LINC01671
Name	long intergenic non-protein coding RNA 1671
Location	21q22.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	BC041455, AP001626.1
Ensembl gene	ENSG00000225431
Ensembl biotype	lncRNA
Entrez	101928233
RNAcentral	URS000081210A — lncRNA, 1726 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000419628

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000419628 — 2 exons

Exon	Start	End
ENSE00003981718	42599280	42600848
ENSE00003981719	42614853	42615094

Expression profiles

Bgee: expression breadth broad, 73 present calls, max score 79.28.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0773 / max 20.6262, expressed in 29 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
190653	0.0415	22
190652	0.0279	14
190651	0.0079	3

Top tissues by expression

73 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adult mammalian kidney	UBERON:0000082	79.28	gold quality
kidney	UBERON:0002113	76.46	gold quality
cortex of kidney	UBERON:0001225	74.85	gold quality
metanephros cortex	UBERON:0010533	74.62	gold quality
right lung	UBERON:0002167	63.64	gold quality
upper lobe of left lung	UBERON:0008952	60.74	gold quality
lung	UBERON:0002048	60.19	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	59.67	gold quality
fallopian tube	UBERON:0003889	59.07	gold quality
leukocyte	CL:0000738	57.67	silver quality
liver	UBERON:0002107	57.54	gold quality
right uterine tube	UBERON:0001302	57.49	gold quality
right lobe of liver	UBERON:0001114	57.38	gold quality
ganglionic eminence	UBERON:0004023	56.64	silver quality
esophagus mucosa	UBERON:0002469	56.49	gold quality
esophagus	UBERON:0001043	56.48	gold quality
urinary bladder	UBERON:0001255	55.62	gold quality
tonsil	UBERON:0002372	55.19	gold quality
gall bladder	UBERON:0002110	53.67	gold quality
left ovary	UBERON:0002119	53.38	gold quality
ectocervix	UBERON:0012249	52.71	gold quality
islet of Langerhans	UBERON:0000006	52.66	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	52.37	gold quality
vagina	UBERON:0000996	51.06	gold quality
prefrontal cortex	UBERON:0000451	50.81	silver quality
thoracic mammary gland	UBERON:0005200	50.72	gold quality
multicellular organism	UBERON:0000468	49.90	gold quality
pancreas	UBERON:0001264	49.75	gold quality
blood	UBERON:0000178	49.20	gold quality
lower esophagus muscularis layer	UBERON:0035833	48.40	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.54

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Results identified one oestrogen-repressed lncRNA gene (BC041455) and one oestrogen-induced lncRNA gene (CR593775). These two primate-specific oestrogen-regulated lncRNAs exert strong and reproducible effects on cell viability, cell growth and cell death of human breast cancer cells. (PMID:28003470)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.