LINC01677

Summary

LINC01677 (long intergenic non-protein coding RNA 1677, HGNC:52465) is a long non-coding RNA gene on chromosome 1p21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52465
Approved symbol	LINC01677
Name	long intergenic non-protein coding RNA 1677
Location	1p21.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233047
Ensembl biotype	lncRNA
Entrez	105378884
RNAcentral	URS0000BC4479 — lncRNA, 993 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000417385, ENST00000429080, ENST00000446693, ENST00000635342, ENST00000635636, ENST00000635713, ENST00000656436

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000417385 — 9 exons

Exon	Start	End
ENSE00001604709	105952504	105952600
ENSE00001609401	106023082	106023212
ENSE00001697156	105952208	105952279
ENSE00001721844	105988450	105988507
ENSE00003785060	105992154	105992344
ENSE00003788354	105953372	105953712
ENSE00003791643	106027203	106027282
ENSE00003876256	105927620	105927714
ENSE00003882929	106027806	106028253

Expression profiles

Bgee: expression breadth broad, 83 present calls, max score 85.28.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0074 / max 7.2174, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
13597	0.0074	3

Top tissues by expression

191 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.28	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	70.26	gold quality
ganglionic eminence	UBERON:0004023	67.95	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.87	gold quality
sural nerve	UBERON:0015488	66.73	gold quality
left testis	UBERON:0004533	63.18	gold quality
sperm	CL:0000019	62.63	silver quality
right testis	UBERON:0004534	62.13	gold quality
testis	UBERON:0000473	61.94	gold quality
tendon of biceps brachii	UBERON:0008188	56.31	gold quality
monocyte	CL:0000576	55.05	gold quality
islet of Langerhans	UBERON:0000006	53.12	gold quality
prefrontal cortex	UBERON:0000451	51.87	gold quality
gall bladder	UBERON:0002110	51.47	gold quality
muscle of leg	UBERON:0001383	49.81	gold quality
buccal mucosa cell	CL:0002336	49.16	gold quality
smooth muscle tissue	UBERON:0001135	48.78	gold quality
gastrocnemius	UBERON:0001388	48.26	gold quality
calcaneal tendon	UBERON:0003701	48.12	silver quality
ectocervix	UBERON:0012249	48.05	gold quality
Brodmann (1909) area 9	UBERON:0013540	47.53	gold quality
pancreas	UBERON:0001264	46.15	gold quality
body of pancreas	UBERON:0001150	45.83	silver quality
lower lobe of lung	UBERON:0008949	45.13	silver quality
left coronary artery	UBERON:0001626	45.00	gold quality
heart left ventricle	UBERON:0002084	44.04	silver quality
apex of heart	UBERON:0002098	43.93	silver quality
right hemisphere of cerebellum	UBERON:0014890	43.81	silver quality
amniotic fluid	UBERON:0000173	43.66	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	43.66	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.77

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.