LINC01678

Summary

LINC01678 (long intergenic non-protein coding RNA 1678, HGNC:52466) is a long non-coding RNA gene on chromosome 21q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52466
Approved symbol	LINC01678
Name	long intergenic non-protein coding RNA 1678
Location	21q22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225331
Ensembl biotype	lncRNA
Entrez	105377138
RNAcentral	URS0000BC4594 — lncRNA, 620 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000411694, ENST00000424921, ENST00000701364

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000411694 — 2 exons

Exon	Start	End
ENSE00004052594	44159825	44160137
ENSE00004052595	44158740	44159354

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 84.43.

FANTOM5 (CAGE): breadth not_expressed, TPM avg 0.0001 / max 0.1509, expressed in 0 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
190731	0.0001	0

Top tissues by expression

131 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.43	gold quality
monocyte	CL:0000576	81.73	gold quality
leukocyte	CL:0000738	81.25	gold quality
sural nerve	UBERON:0015488	81.24	gold quality
granulocyte	CL:0000094	78.79	gold quality
vermiform appendix	UBERON:0001154	74.14	gold quality
blood	UBERON:0000178	73.81	gold quality
spleen	UBERON:0002106	72.69	gold quality
mucosa of stomach	UBERON:0001199	71.20	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	71.18	gold quality
bone marrow cell	CL:0002092	70.87	gold quality
subcutaneous adipose tissue	UBERON:0002190	69.72	gold quality
putamen	UBERON:0001874	69.36	gold quality
substantia nigra	UBERON:0002038	69.24	gold quality
adipose tissue	UBERON:0001013	69.17	gold quality
upper lobe of left lung	UBERON:0008952	69.11	gold quality
lower esophagus muscularis layer	UBERON:0035833	68.92	gold quality
lower esophagus	UBERON:0013473	68.85	gold quality
lymph node	UBERON:0000029	68.70	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	68.64	gold quality
right lung	UBERON:0002167	68.60	gold quality
omental fat pad	UBERON:0010414	68.42	gold quality
muscle layer of sigmoid colon	UBERON:0035805	68.10	gold quality
bone marrow	UBERON:0002371	67.93	gold quality
lung	UBERON:0002048	67.53	gold quality
gall bladder	UBERON:0002110	67.51	gold quality
right ovary	UBERON:0002118	67.49	gold quality
tibial nerve	UBERON:0001323	67.39	gold quality
heart left ventricle	UBERON:0002084	67.39	gold quality
descending thoracic aorta	UBERON:0002345	67.16	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.85

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.