LINC01684

Summary

LINC01684 (long intergenic non-protein coding RNA 1684, HGNC:52472) is a long non-coding RNA gene on chromosome 21q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52472
Approved symbol	LINC01684
Name	long intergenic non-protein coding RNA 1684
Location	21q21.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	lnc-JAM2-6
Ensembl gene	ENSG00000237484
Ensembl biotype	lncRNA
Entrez	105372751
RNAcentral	URS0000A773AE — lncRNA, 2236 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 35 — 35 lncRNA

ENST00000415182, ENST00000423581, ENST00000453784, ENST00000653166, ENST00000653413, ENST00000653855, ENST00000654158, ENST00000654771, ENST00000655039, ENST00000655241, ENST00000655294, ENST00000655505, ENST00000655533, ENST00000656088, ENST00000656122, ENST00000656780, ENST00000656842, ENST00000657079, ENST00000657522, ENST00000657774, ENST00000659824, ENST00000662917, ENST00000663985, ENST00000666492, ENST00000668315, ENST00000668910, ENST00000670142, ENST00000671574, ENST00000701591, ENST00000724112, ENST00000826644, ENST00000826645, ENST00000826646, ENST00000826647, ENST00000826648

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000415182 — 3 exons

Exon	Start	End
ENSE00001602478	24545995	24547942
ENSE00001656340	24530664	24530767
ENSE00001753281	24428781	24428904

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 83.96.

FANTOM5 (CAGE): breadth broad, TPM avg 0.6914 / max 36.6086, expressed in 264 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
188634	0.5930	236
188635	0.0984	43

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.96	gold quality
spleen	UBERON:0002106	76.19	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	75.19	gold quality
lymph node	UBERON:0000029	75.01	gold quality
endometrium	UBERON:0001295	70.35	gold quality
bone marrow cell	CL:0002092	69.76	silver quality
stromal cell of endometrium	CL:0002255	68.91	gold quality
leukocyte	CL:0000738	67.83	gold quality
granulocyte	CL:0000094	67.65	gold quality
monocyte	CL:0000576	67.57	gold quality
tonsil	UBERON:0002372	67.05	gold quality
bone marrow	UBERON:0002371	65.68	gold quality
ventricular zone	UBERON:0003053	65.63	gold quality
vermiform appendix	UBERON:0001154	65.16	gold quality
calcaneal tendon	UBERON:0003701	64.30	gold quality
smooth muscle tissue	UBERON:0001135	63.32	gold quality
muscle tissue	UBERON:0002385	62.44	gold quality
blood	UBERON:0000178	61.28	gold quality
subcutaneous adipose tissue	UBERON:0002190	60.49	gold quality
adipose tissue	UBERON:0001013	60.08	gold quality
omental fat pad	UBERON:0010414	59.34	gold quality
liver	UBERON:0002107	58.29	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.10	gold quality
right lobe of liver	UBERON:0001114	57.55	gold quality
placenta	UBERON:0001987	57.10	gold quality
urinary bladder	UBERON:0001255	56.90	gold quality
body of stomach	UBERON:0001161	56.85	gold quality
stomach	UBERON:0000945	56.72	gold quality
ganglionic eminence	UBERON:0004023	56.66	gold quality
right adrenal gland cortex	UBERON:0035827	56.33	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.24

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.