LINC01687

Summary

LINC01687 (long intergenic non-protein coding RNA 1687, HGNC:52474) is a long non-coding RNA gene on chromosome 21q21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52474
Approved symbol	LINC01687
Name	long intergenic non-protein coding RNA 1687
Location	21q21.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233215
Ensembl biotype	lncRNA
Entrez	101927843
RNAcentral	URS0000353535 — lncRNA, 897 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000416327, ENST00000419467, ENST00000420255, ENST00000656955, ENST00000666229, ENST00000667392, ENST00000667604, ENST00000669715, ENST00000833435

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416327 — 3 exons

Exon	Start	End
ENSE00001621289	22016300	22016410
ENSE00001644507	22017888	22018156
ENSE00001772640	22008944	22009358

Expression profiles

Bgee: expression breadth broad, 73 present calls, max score 80.68.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0732 / max 21.7826, expressed in 13 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
189907	0.0732	13

Top tissues by expression

177 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.68	gold quality
transverse colon	UBERON:0001157	75.19	gold quality
right lobe of liver	UBERON:0001114	75.02	gold quality
rectum	UBERON:0001052	73.31	gold quality
liver	UBERON:0002107	67.74	gold quality
colonic epithelium	UBERON:0000397	66.76	silver quality
colon	UBERON:0001155	64.70	gold quality
mucosa of transverse colon	UBERON:0004991	64.62	gold quality
large intestine	UBERON:0000059	63.68	gold quality
vermiform appendix	UBERON:0001154	62.80	gold quality
intestine	UBERON:0000160	60.84	gold quality
muscle layer of sigmoid colon	UBERON:0035805	59.39	gold quality
caecum	UBERON:0001153	59.16	gold quality
body of pancreas	UBERON:0001150	57.69	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	57.04	gold quality
cortex of kidney	UBERON:0001225	56.34	gold quality
pancreas	UBERON:0001264	55.49	gold quality
metanephros cortex	UBERON:0010533	54.03	gold quality
smooth muscle tissue	UBERON:0001135	53.85	gold quality
monocyte	CL:0000576	52.93	gold quality
small intestine Peyer’s patch	UBERON:0003454	52.93	gold quality
hindlimb stylopod muscle	UBERON:0004252	51.33	gold quality
islet of Langerhans	UBERON:0000006	50.90	gold quality
small intestine	UBERON:0002108	50.50	gold quality
adult mammalian kidney	UBERON:0000082	50.28	gold quality
metanephros	UBERON:0000081	49.94	gold quality
buccal mucosa cell	CL:0002336	49.40	gold quality
kidney	UBERON:0002113	48.57	gold quality
tendon of biceps brachii	UBERON:0008188	48.36	gold quality
gall bladder	UBERON:0002110	47.81	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.24

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.