LINC01689

Summary

LINC01689 (long intergenic non-protein coding RNA 1689, HGNC:52476) is a long non-coding RNA gene on chromosome 21q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52476
Approved symbol	LINC01689
Name	long intergenic non-protein coding RNA 1689
Location	21q21.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	AP000469.2
Ensembl gene	ENSG00000224832
Ensembl biotype	lncRNA
Entrez	101927869
RNAcentral	URS000075D9EF — lncRNA, 2028 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000416218, ENST00000642623

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416218 — 4 exons

Exon	Start	End
ENSE00001645645	24308216	24308333
ENSE00001701869	24307619	24307759
ENSE00001775295	24304550	24306169
ENSE00001783728	24321250	24321377

Expression profiles

Bgee: expression breadth broad, 11 present calls, max score 92.47.

Top tissues by expression

170 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.47	gold quality
monocyte	CL:0000576	53.09	gold quality
upper leg skin	UBERON:0004262	49.95	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	48.26	silver quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
testis	UBERON:0000473	43.34	gold quality
secondary oocyte	CL:0000655	42.57	gold quality
blood	UBERON:0000178	42.25	gold quality
heart left ventricle	UBERON:0002084	41.97	gold quality
upper lobe of lung	UBERON:0008948	41.91	silver quality
lower lobe of lung	UBERON:0008949	41.85	silver quality
vastus lateralis	UBERON:0001379	41.41	gold quality
quadriceps femoris	UBERON:0001377	41.37	gold quality
prefrontal cortex	UBERON:0000451	41.35	gold quality
adult mammalian kidney	UBERON:0000082	41.34	gold quality
superficial temporal artery	UBERON:0001614	41.33	gold quality
cardiac ventricle	UBERON:0002082	41.15	gold quality
bone marrow	UBERON:0002371	41.14	gold quality
skeletal muscle tissue	UBERON:0001134	41.10	gold quality
palpebral conjunctiva	UBERON:0001812	41.10	gold quality
adrenal gland	UBERON:0002369	41.08	gold quality
mucosa of paranasal sinus	UBERON:0005030	40.98	gold quality
amniotic fluid	UBERON:0000173	40.69	gold quality
nasal cavity mucosa	UBERON:0001826	40.63	gold quality
jejunal mucosa	UBERON:0000399	40.59	gold quality
endometrium	UBERON:0001295	40.57	gold quality
biceps brachii	UBERON:0001507	40.57	gold quality
liver	UBERON:0002107	40.51	gold quality
adipose tissue	UBERON:0001013	40.50	gold quality
epithelium of nasopharynx	UBERON:0001951	40.45	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.78

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.