LINC01694

Summary

LINC01694 (long intergenic non-protein coding RNA 1694, HGNC:52481) is a long non-coding RNA gene on chromosome 21q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52481
Approved symbol	LINC01694
Name	long intergenic non-protein coding RNA 1694
Location	21q22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233922
Ensembl biotype	lncRNA
Entrez	105372840
RNAcentral	URS0000BC44E9 — lncRNA, 6735 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000424569, ENST00000441095, ENST00000662558, ENST00000671273, ENST00000685333, ENST00000820344, ENST00000820345, ENST00000820346, ENST00000820347

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000424569 — 3 exons

Exon	Start	End
ENSE00001678177	45595573	45595661
ENSE00004226232	45593654	45593708
ENSE00004226240	45596391	45597091

Expression profiles

Bgee: expression breadth ubiquitous, 154 present calls, max score 80.01.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2312 / max 38.8803, expressed in 95 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
189572	0.2312	95

Top tissues by expression

241 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.01	gold quality
colonic epithelium	UBERON:0000397	78.46	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	73.91	gold quality
cortical plate	UBERON:0005343	66.02	gold quality
bone marrow cell	CL:0002092	65.28	silver quality
ventricular zone	UBERON:0003053	63.98	gold quality
cerebellar hemisphere	UBERON:0002245	60.08	gold quality
cerebellar cortex	UBERON:0002129	60.02	gold quality
right hemisphere of cerebellum	UBERON:0014890	59.35	gold quality
ganglionic eminence	UBERON:0004023	58.89	gold quality
cerebellum	UBERON:0002037	58.66	gold quality
body of pancreas	UBERON:0001150	57.96	gold quality
stromal cell of endometrium	CL:0002255	57.57	gold quality
right ovary	UBERON:0002118	57.36	gold quality
monocyte	CL:0000576	57.26	gold quality
leukocyte	CL:0000738	56.90	gold quality
left ovary	UBERON:0002119	56.72	gold quality
putamen	UBERON:0001874	56.62	gold quality
vermiform appendix	UBERON:0001154	56.38	gold quality
adrenal tissue	UBERON:0018303	56.08	gold quality
calcaneal tendon	UBERON:0003701	55.94	gold quality
spleen	UBERON:0002106	55.67	gold quality
ovary	UBERON:0000992	55.62	gold quality
pancreas	UBERON:0001264	55.53	gold quality
lymph node	UBERON:0000029	54.97	gold quality
sural nerve	UBERON:0015488	54.74	silver quality
muscle layer of sigmoid colon	UBERON:0035805	54.72	gold quality
corpus callosum	UBERON:0002336	53.83	gold quality
body of uterus	UBERON:0009853	53.51	gold quality
caudate nucleus	UBERON:0001873	53.18	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.25

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Knockdown of LINC01694 inhibits growth of gallbladder cancer cells via miR-340-5p/Sox4. (PMID:32270853)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.