LINC01711

Summary

LINC01711 (long intergenic non-protein coding RNA 1711, HGNC:28663) is a long non-coding RNA gene on chromosome 20q13.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:28663
Approved symbol	LINC01711
Name	long intergenic non-protein coding RNA 1711
Location	20q13.32
Locus type	RNA, long non-coding
Status	Approved
Aliases	MGC4294
Ensembl gene	ENSG00000268941
Ensembl biotype	lncRNA
Entrez	79160
RNAcentral	URS000075DF8A — lncRNA, 984 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000598340

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000598340 — 1 exons

Exon	Start	End
ENSE00003010847	58634772	58635738

Expression profiles

Bgee: expression breadth ubiquitous, 118 present calls, max score 64.69.

Top tissues by expression

228 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
stromal cell of endometrium	CL:0002255	64.69	gold quality
buccal mucosa cell	CL:0002336	63.48	gold quality
ventricular zone	UBERON:0003053	62.20	gold quality
cartilage tissue	UBERON:0002418	60.77	gold quality
cortical plate	UBERON:0005343	60.01	gold quality
ganglionic eminence	UBERON:0004023	59.55	gold quality
endothelial cell	CL:0000115	58.29	gold quality
secondary oocyte	CL:0000655	57.27	gold quality
tibia	UBERON:0000979	56.31	gold quality
hypothalamus	UBERON:0001898	56.17	gold quality
gall bladder	UBERON:0002110	56.02	gold quality
islet of Langerhans	UBERON:0000006	55.24	gold quality
middle temporal gyrus	UBERON:0002771	54.54	gold quality
descending thoracic aorta	UBERON:0002345	54.21	gold quality
tendon of biceps brachii	UBERON:0008188	53.62	gold quality
Brodmann (1909) area 23	UBERON:0013554	53.41	gold quality
primary visual cortex	UBERON:0002436	53.07	gold quality
nasal cavity epithelium	UBERON:0005384	52.60	gold quality
pancreas	UBERON:0001264	52.23	gold quality
tendon	UBERON:0000043	52.12	gold quality
Ammon’s horn	UBERON:0001954	51.84	gold quality
adult mammalian kidney	UBERON:0000082	51.24	gold quality
amygdala	UBERON:0001876	50.55	gold quality
minor salivary gland	UBERON:0001830	50.28	gold quality
saliva-secreting gland	UBERON:0001044	49.92	gold quality
blood vessel layer	UBERON:0004797	49.29	gold quality
prefrontal cortex	UBERON:0000451	49.22	gold quality
muscle of leg	UBERON:0001383	49.07	gold quality
vermiform appendix	UBERON:0001154	49.00	gold quality
mouth mucosa	UBERON:0003729	48.97	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.49

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 3)

• Exosomal lncRNA LINC01711 facilitates metastasis of esophageal squamous cell carcinoma via the miR-326/FSCN1 axis. (PMID:34370713)
• LINC01711 promotes transforming growth factor-beta (TGF-beta) induced invasion in glioblastoma multiforme (GBM) by acting as a competing endogenous RNA for miR-34a and promoting ZEB1 expression. (PMID:36341927)
• SNAI1-activated long non-coding RNA LINC01711 promotes hepatic fibrosis cell proliferation and migration by regulating XYLT1. (PMID:36871637)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.