LINC01721

Summary

LINC01721 (long intergenic non-protein coding RNA 1721, HGNC:52508) is a long non-coding RNA gene on chromosome 20p11.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52508
Approved symbol	LINC01721
Name	long intergenic non-protein coding RNA 1721
Location	20p11.21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230133
Ensembl biotype	lncRNA
Entrez	400839
RNAcentral	URS00004EC2FD — lncRNA, 2376 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000457274, ENST00000657180, ENST00000664459, ENST00000667083, ENST00000669143, ENST00000753590, ENST00000753591

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000457274 — 4 exons

Exon	Start	End
ENSE00001641483	24199767	24199834
ENSE00001650057	24219623	24219702
ENSE00001696844	24223704	24224588
ENSE00001707060	24211349	24212691

Expression profiles

Bgee: expression breadth broad, 76 present calls, max score 75.28.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0849 / max 28.7072, expressed in 30 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
183892	0.0849	30

Top tissues by expression

76 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.28	gold quality
sural nerve	UBERON:0015488	68.40	silver quality
superior frontal gyrus	UBERON:0002661	62.32	gold quality
primary visual cortex	UBERON:0002436	61.23	gold quality
prefrontal cortex	UBERON:0000451	59.50	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.44	silver quality
frontal cortex	UBERON:0001870	56.26	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	54.69	gold quality
Brodmann (1909) area 9	UBERON:0013540	54.33	gold quality
cerebral cortex	UBERON:0000956	54.13	gold quality
monocyte	CL:0000576	53.29	gold quality
liver	UBERON:0002107	53.11	gold quality
right lobe of liver	UBERON:0001114	52.65	gold quality
endometrium	UBERON:0001295	52.46	silver quality
brain	UBERON:0000955	51.81	gold quality
right frontal lobe	UBERON:0002810	51.65	gold quality
skeletal muscle tissue	UBERON:0001134	51.42	silver quality
corpus callosum	UBERON:0002336	50.84	gold quality
right hemisphere of cerebellum	UBERON:0014890	49.19	gold quality
calcaneal tendon	UBERON:0003701	49.11	silver quality
blood	UBERON:0000178	49.00	silver quality
islet of Langerhans	UBERON:0000006	48.55	silver quality
vermiform appendix	UBERON:0001154	48.20	gold quality
muscle of leg	UBERON:0001383	47.95	silver quality
adrenal tissue	UBERON:0018303	47.49	silver quality
caudate nucleus	UBERON:0001873	47.22	gold quality
multicellular organism	UBERON:0000468	45.78	gold quality
small intestine	UBERON:0002108	45.70	silver quality
anterior cingulate cortex	UBERON:0009835	45.39	gold quality
gall bladder	UBERON:0002110	44.79	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.