LINC01728

Summary

LINC01728 (long intergenic non-protein coding RNA 1728, HGNC:52516) is a long non-coding RNA gene on chromosome 20q13.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52516
Approved symbol	LINC01728
Name	long intergenic non-protein coding RNA 1728
Location	20q13.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233277
Ensembl biotype	lncRNA
Entrez	105372626
RNAcentral	URS0000A76B30 — lncRNA, 537 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000428529, ENST00000814368

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000428529 — 2 exons

Exon	Start	End
ENSE00004215330	43894639	43894797
ENSE00004215331	43895023	43895468

Expression profiles

Bgee: expression breadth broad, 39 present calls, max score 88.32.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0163 / max 18.9456, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
184684	0.0163	3

Top tissues by expression

39 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.32	gold quality
muscle tissue	UBERON:0002385	67.60	gold quality
left testis	UBERON:0004533	67.51	gold quality
testis	UBERON:0000473	66.69	gold quality
right testis	UBERON:0004534	66.37	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.52	gold quality
Ammon’s horn	UBERON:0001954	65.49	gold quality
multicellular organism	UBERON:0000468	60.45	gold quality
monocyte	CL:0000576	55.95	gold quality
blood	UBERON:0000178	51.94	gold quality
islet of Langerhans	UBERON:0000006	50.96	gold quality
spleen	UBERON:0002106	47.92	gold quality
gastrocnemius	UBERON:0001388	47.03	gold quality
tibial artery	UBERON:0007610	46.62	gold quality
heart left ventricle	UBERON:0002084	46.11	gold quality
tibial nerve	UBERON:0001323	46.05	gold quality
body of stomach	UBERON:0001161	45.90	gold quality
right hemisphere of cerebellum	UBERON:0014890	45.01	silver quality
lower esophagus muscularis layer	UBERON:0035833	44.59	silver quality
skin of abdomen	UBERON:0001416	43.52	gold quality
right adrenal gland	UBERON:0001233	43.43	silver quality
skin of leg	UBERON:0001511	42.93	gold quality
vagina	UBERON:0000996	42.83	silver quality
prostate gland	UBERON:0002367	42.65	gold quality
small intestine Peyer’s patch	UBERON:0003454	42.62	silver quality
esophagus mucosa	UBERON:0002469	41.98	silver quality
ascending aorta	UBERON:0001496	41.87	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	41.77	gold quality
thoracic aorta	UBERON:0001515	41.70	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	41.45	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.