LINC01730

Summary

LINC01730 (long intergenic non-protein coding RNA 1730, HGNC:52518) is a long non-coding RNA gene on chromosome 20p13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52518
Approved symbol	LINC01730
Name	long intergenic non-protein coding RNA 1730
Location	20p13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000275491
Ensembl biotype	lncRNA
Entrez	101929125
RNAcentral	URS000075AC7B — lncRNA, 728 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000613868, ENST00000716606, ENST00000716607, ENST00000716608, ENST00000716609

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000613868 — 4 exons

Exon	Start	End
ENSE00003723554	3809897	3810014
ENSE00003724068	3811530	3811741
ENSE00004030241	3808357	3808602
ENSE00004030249	3812168	3812434

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 82.27.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1125 / max 22.8407, expressed in 34 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
183232	0.1125	34

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.27	silver quality
quadriceps femoris	UBERON:0001377	73.94	gold quality
cerebellar hemisphere	UBERON:0002245	72.05	gold quality
cerebellar cortex	UBERON:0002129	71.89	gold quality
cerebellum	UBERON:0002037	71.79	gold quality
right hemisphere of cerebellum	UBERON:0014890	71.48	gold quality
blood	UBERON:0000178	71.02	gold quality
cerebellar vermis	UBERON:0004720	67.55	gold quality
lymph node	UBERON:0000029	64.47	gold quality
granulocyte	CL:0000094	64.28	gold quality
right lung	UBERON:0002167	64.17	gold quality
thymus	UBERON:0002370	63.27	silver quality
spleen	UBERON:0002106	63.25	gold quality
upper lobe of left lung	UBERON:0008952	62.93	gold quality
cortical plate	UBERON:0005343	62.39	gold quality
lung	UBERON:0002048	61.30	gold quality
adenohypophysis	UBERON:0002196	61.17	gold quality
bone marrow	UBERON:0002371	61.08	gold quality
nucleus accumbens	UBERON:0001882	60.05	gold quality
lower esophagus muscularis layer	UBERON:0035833	59.70	gold quality
pituitary gland	UBERON:0000007	59.64	gold quality
lower esophagus	UBERON:0013473	59.61	gold quality
caudate nucleus	UBERON:0001873	59.26	gold quality
putamen	UBERON:0001874	59.16	gold quality
tonsil	UBERON:0002372	58.87	gold quality
stromal cell of endometrium	CL:0002255	58.69	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	58.61	gold quality
muscle layer of sigmoid colon	UBERON:0035805	58.60	gold quality
left uterine tube	UBERON:0001303	58.36	gold quality
vermiform appendix	UBERON:0001154	58.17	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.53

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.