LINC01736

Summary

LINC01736 (long intergenic non-protein coding RNA 1736, HGNC:52524) is a long non-coding RNA gene on chromosome 1q42.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52524
Approved symbol	LINC01736
Name	long intergenic non-protein coding RNA 1736
Location	1q42.13
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-552D4.1
Ensembl gene	ENSG00000228058
Ensembl biotype	lncRNA
Entrez	101927532
RNAcentral	URS0000A774BF — lncRNA, 678 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000445339, ENST00000660480, ENST00000661272, ENST00000663288, ENST00000692439, ENST00000702654, ENST00000847462, ENST00000847463, ENST00000847464, ENST00000847465, ENST00000847466

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000445339 — 2 exons

Exon	Start	End
ENSE00001604720	230006773	230007162
ENSE00001750028	230002730	230002993

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 82.14.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.5086 / max 67.4203, expressed in 84 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
9012	0.1929	66
9013	0.1601	58
9014	0.1025	44
9015	0.0530	30

Top tissues by expression

112 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
C1 segment of cervical spinal cord	UBERON:0006469	82.14	gold quality
substantia nigra	UBERON:0002038	79.70	gold quality
hypothalamus	UBERON:0001898	71.50	gold quality
Ammon’s horn	UBERON:0001954	71.15	gold quality
corpus callosum	UBERON:0002336	71.12	gold quality
Brodmann (1909) area 9	UBERON:0013540	69.84	gold quality
temporal lobe	UBERON:0001871	69.81	gold quality
amygdala	UBERON:0001876	69.57	gold quality
prefrontal cortex	UBERON:0000451	68.68	gold quality
monocyte	CL:0000576	68.36	gold quality
leukocyte	CL:0000738	68.23	gold quality
caudate nucleus	UBERON:0001873	67.33	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	66.92	gold quality
putamen	UBERON:0001874	66.87	gold quality
cerebral cortex	UBERON:0000956	66.73	gold quality
blood	UBERON:0000178	66.44	gold quality
nucleus accumbens	UBERON:0001882	66.32	gold quality
frontal cortex	UBERON:0001870	65.76	gold quality
brain	UBERON:0000955	65.56	gold quality
anterior cingulate cortex	UBERON:0009835	64.95	gold quality
ganglionic eminence	UBERON:0004023	64.62	gold quality
lymph node	UBERON:0000029	63.57	gold quality
right adrenal gland cortex	UBERON:0035827	62.98	gold quality
ventricular zone	UBERON:0003053	62.92	gold quality
superior frontal gyrus	UBERON:0002661	62.56	gold quality
granulocyte	CL:0000094	61.77	gold quality
primary visual cortex	UBERON:0002436	61.41	gold quality
right frontal lobe	UBERON:0002810	61.37	gold quality
adrenal gland	UBERON:0002369	59.52	gold quality
left adrenal gland	UBERON:0001234	59.40	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.51

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• RP11-552D4.1: a novel m6a-related LncRNA associated with immune status in glioblastoma. (PMID:35852867)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.