LINC01749

Summary

LINC01749 (long intergenic non-protein coding RNA 1749, HGNC:52537) is a long non-coding RNA gene on chromosome 20q13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52537
Approved symbol	LINC01749
Name	long intergenic non-protein coding RNA 1749
Location	20q13.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000272259
Ensembl biotype	lncRNA
Entrez	63930
RNAcentral	URS00004CB359 — lncRNA, 3408 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000606208, ENST00000607802, ENST00000793343

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000606208 — 2 exons

Exon	Start	End
ENSE00003696839	63009383	63009473
ENSE00003699647	63083282	63084133

Expression profiles

Bgee: expression breadth broad, 37 present calls, max score 60.19.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2754 / max 89.4180, expressed in 31 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
185787	0.1664	26
185786	0.0552	15
185788	0.0538	15

Top tissues by expression

37 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
ganglionic eminence	UBERON:0004023	60.19	gold quality
cerebellar hemisphere	UBERON:0002245	55.69	gold quality
cerebellum	UBERON:0002037	55.65	gold quality
cerebellar cortex	UBERON:0002129	55.60	gold quality
right hemisphere of cerebellum	UBERON:0014890	55.56	gold quality
pituitary gland	UBERON:0000007	51.25	gold quality
prefrontal cortex	UBERON:0000451	51.07	gold quality
skin of leg	UBERON:0001511	50.95	gold quality
monocyte	CL:0000576	49.43	silver quality
caudate nucleus	UBERON:0001873	48.36	gold quality
blood	UBERON:0000178	47.18	silver quality
spleen	UBERON:0002106	46.95	gold quality
saliva-secreting gland	UBERON:0001044	46.04	gold quality
transverse colon	UBERON:0001157	45.80	gold quality
lymph node	UBERON:0000029	44.90	silver quality
cerebral cortex	UBERON:0000956	44.25	silver quality
Brodmann (1909) area 9	UBERON:0013540	43.67	gold quality
right atrium auricular region	UBERON:0006631	43.12	silver quality
small intestine	UBERON:0002108	43.00	silver quality
superior frontal gyrus	UBERON:0002661	41.94	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	41.74	gold quality
amygdala	UBERON:0001876	41.56	gold quality
stomach	UBERON:0000945	41.53	silver quality
Ammon’s horn	UBERON:0001954	41.53	silver quality
omental fat pad	UBERON:0010414	41.20	gold quality
body of stomach	UBERON:0001161	39.94	silver quality
subcutaneous adipose tissue	UBERON:0002190	39.90	silver quality
small intestine Peyer’s patch	UBERON:0003454	39.28	silver quality
right frontal lobe	UBERON:0002810	39.09	silver quality
skin of abdomen	UBERON:0001416	37.76	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.