LINC01750

Summary

LINC01750 (long intergenic non-protein coding RNA 1750, HGNC:52538) is a long non-coding RNA gene on chromosome 1p13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52538
Approved symbol	LINC01750
Name	long intergenic non-protein coding RNA 1750
Location	1p13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231437
Ensembl biotype	lncRNA
Entrez	643355
RNAcentral	URS000054BD20 — lncRNA, 3068 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 18 — 18 lncRNA

ENST00000428461, ENST00000438293, ENST00000442751, ENST00000748684, ENST00000748685, ENST00000748686, ENST00000748687, ENST00000748688, ENST00000748689, ENST00000748690, ENST00000748691, ENST00000748692, ENST00000748693, ENST00000748694, ENST00000748695, ENST00000748696, ENST00000748697, ENST00000748698

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000428461 — 4 exons

Exon	Start	End
ENSE00004091735	112007051	112007099
ENSE00004091743	112007908	112008406
ENSE00004091744	111990568	111991187
ENSE00004091746	111990296	111990398

Expression profiles

Bgee: expression breadth ubiquitous, 148 present calls, max score 84.83.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0363 / max 18.3978, expressed in 11 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
4660	0.0363	11

Top tissues by expression

232 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.83	gold quality
buccal mucosa cell	CL:0002336	83.20	gold quality
right hemisphere of cerebellum	UBERON:0014890	76.46	gold quality
cerebellar hemisphere	UBERON:0002245	75.29	gold quality
cerebellar cortex	UBERON:0002129	75.22	gold quality
cerebellum	UBERON:0002037	73.42	gold quality
prefrontal cortex	UBERON:0000451	73.18	gold quality
Brodmann (1909) area 9	UBERON:0013540	72.70	gold quality
right frontal lobe	UBERON:0002810	72.67	gold quality
anterior cingulate cortex	UBERON:0009835	72.28	gold quality
nucleus accumbens	UBERON:0001882	71.07	gold quality
neocortex	UBERON:0001950	68.07	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	67.59	gold quality
frontal cortex	UBERON:0001870	67.50	gold quality
caudate nucleus	UBERON:0001873	67.48	gold quality
amygdala	UBERON:0001876	67.44	gold quality
putamen	UBERON:0001874	66.83	gold quality
hindlimb stylopod muscle	UBERON:0004252	66.62	gold quality
ventricular zone	UBERON:0003053	66.07	gold quality
right atrium auricular region	UBERON:0006631	65.98	gold quality
hypothalamus	UBERON:0001898	65.95	gold quality
apex of heart	UBERON:0002098	65.49	gold quality
right lobe of liver	UBERON:0001114	65.37	gold quality
cardiac atrium	UBERON:0002081	65.33	gold quality
ganglionic eminence	UBERON:0004023	65.14	gold quality
monocyte	CL:0000576	64.89	gold quality
cerebral cortex	UBERON:0000956	64.55	gold quality
brain	UBERON:0000955	64.32	gold quality
leukocyte	CL:0000738	64.15	gold quality
forebrain	UBERON:0001890	63.77	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.90

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.