LINC01753

Summary

LINC01753 (long intergenic non-protein coding RNA 1753, HGNC:52541) is a long non-coding RNA gene on chromosome 1p32.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52541
Approved symbol	LINC01753
Name	long intergenic non-protein coding RNA 1753
Location	1p32.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230250
Ensembl biotype	lncRNA
Entrez	105378739
RNAcentral	URS0000BC441D — lncRNA, 644 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000458145, ENST00000635532, ENST00000665254, ENST00000671610, ENST00000745966, ENST00000745967

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000458145 — 3 exons

Exon	Start	End
ENSE00001701487	55921365	55921411
ENSE00001800179	55915603	55916144
ENSE00003787398	55944916	55944974

Expression profiles

Bgee: expression breadth broad, 40 present calls, max score 90.83.

Top tissues by expression

165 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	90.83	gold quality
bone marrow cell	CL:0002092	77.73	silver quality
left testis	UBERON:0004533	61.85	gold quality
right testis	UBERON:0004534	61.75	gold quality
testis	UBERON:0000473	60.09	gold quality
vena cava	UBERON:0004087	59.75	gold quality
mucosa of paranasal sinus	UBERON:0005030	59.20	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	57.76	gold quality
monocyte	CL:0000576	57.62	gold quality
epithelium of nasopharynx	UBERON:0001951	57.31	gold quality
islet of Langerhans	UBERON:0000006	55.38	gold quality
biceps brachii	UBERON:0001507	55.14	gold quality
gingival epithelium	UBERON:0001949	54.46	gold quality
substantia nigra pars reticulata	UBERON:0001966	54.05	gold quality
amniotic fluid	UBERON:0000173	53.41	gold quality
left coronary artery	UBERON:0001626	53.36	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.80	gold quality
pigmented layer of retina	UBERON:0001782	52.61	gold quality
mammary duct	UBERON:0001765	52.48	gold quality
calcaneal tendon	UBERON:0003701	51.43	silver quality
oral cavity	UBERON:0000167	51.31	gold quality
skeletal muscle tissue	UBERON:0001134	50.97	gold quality
placenta	UBERON:0001987	50.29	silver quality
gingiva	UBERON:0001828	50.26	gold quality
quadriceps femoris	UBERON:0001377	49.50	gold quality
vastus lateralis	UBERON:0001379	49.21	gold quality
lateral nuclear group of thalamus	UBERON:0002736	48.56	gold quality
gastrocnemius	UBERON:0001388	48.21	gold quality
tonsil	UBERON:0002372	47.86	gold quality
ventral tegmental area	UBERON:0002691	47.12	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.62

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.