LINC01754

Summary

LINC01754 (long intergenic non-protein coding RNA 1754, HGNC:52542) is a long non-coding RNA gene on chromosome 20q13.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52542
Approved symbol	LINC01754
Name	long intergenic non-protein coding RNA 1754
Location	20q13.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224565
Ensembl biotype	lncRNA
Entrez	102723442
RNAcentral	URS0000BC43A9 — lncRNA, 2719 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000437920, ENST00000655691, ENST00000726880, ENST00000726881, ENST00000726882, ENST00000726883, ENST00000726884

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000437920 — 4 exons

Exon	Start	End
ENSE00001630335	47397149	47397345
ENSE00001642710	47412070	47412327
ENSE00003866721	47391925	47392097
ENSE00004051873	47411268	47411393

Expression profiles

Bgee: expression breadth broad, 98 present calls, max score 87.49.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0954 / max 49.0512, expressed in 34 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
187631	0.0448	15
187633	0.0232	13
187635	0.0117	7
187634	0.0096	4
187632	0.0061	4

Top tissues by expression

98 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.49	gold quality
bone marrow cell	CL:0002092	70.95	silver quality
body of pancreas	UBERON:0001150	67.64	gold quality
pancreas	UBERON:0001264	65.36	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.59	gold quality
skeletal muscle tissue	UBERON:0001134	64.19	gold quality
tonsil	UBERON:0002372	64.03	gold quality
muscle of leg	UBERON:0001383	61.64	gold quality
bone marrow	UBERON:0002371	60.56	silver quality
gastrocnemius	UBERON:0001388	60.35	gold quality
islet of Langerhans	UBERON:0000006	60.12	gold quality
lymph node	UBERON:0000029	59.78	gold quality
spleen	UBERON:0002106	58.64	gold quality
vermiform appendix	UBERON:0001154	56.62	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	56.28	silver quality
leukocyte	CL:0000738	55.50	gold quality
duodenum	UBERON:0002114	53.79	gold quality
blood	UBERON:0000178	53.49	gold quality
monocyte	CL:0000576	53.25	gold quality
prefrontal cortex	UBERON:0000451	51.74	gold quality
small intestine	UBERON:0002108	50.84	gold quality
multicellular organism	UBERON:0000468	50.78	gold quality
gall bladder	UBERON:0002110	50.76	gold quality
small intestine Peyer’s patch	UBERON:0003454	50.54	gold quality
mucosa of transverse colon	UBERON:0004991	49.85	gold quality
endometrium	UBERON:0001295	49.73	gold quality
liver	UBERON:0002107	48.83	gold quality
placenta	UBERON:0001987	48.11	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	48.09	gold quality
urinary bladder	UBERON:0001255	47.86	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.03

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.