LINC01757

Summary

LINC01757 (long intergenic non-protein coding RNA 1757, HGNC:52546) is a long non-coding RNA gene on chromosome 1p36.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52546
Approved symbol	LINC01757
Name	long intergenic non-protein coding RNA 1757
Location	1p36.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228105
Ensembl biotype	lncRNA
Entrez	105376827
RNAcentral	URS0000BC45AC — lncRNA, 492 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000435552, ENST00000659784, ENST00000734304

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000435552 — 2 exons

Exon	Start	End
ENSE00001674715	20244296	20244655
ENSE00004066322	20242992	20243214

Expression profiles

Bgee: expression breadth broad, 39 present calls, max score 78.73.

Top tissues by expression

39 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.73	gold quality
cortex of kidney	UBERON:0001225	78.59	gold quality
nucleus accumbens	UBERON:0001882	57.30	gold quality
blood	UBERON:0000178	55.88	gold quality
right testis	UBERON:0004534	55.54	gold quality
monocyte	CL:0000576	54.62	gold quality
testis	UBERON:0000473	54.61	gold quality
left testis	UBERON:0004533	54.43	gold quality
sural nerve	UBERON:0015488	53.76	silver quality
superior frontal gyrus	UBERON:0002661	53.68	gold quality
multicellular organism	UBERON:0000468	51.08	gold quality
islet of Langerhans	UBERON:0000006	49.83	gold quality
ascending aorta	UBERON:0001496	49.56	gold quality
right lobe of liver	UBERON:0001114	47.46	silver quality
amygdala	UBERON:0001876	46.95	gold quality
prefrontal cortex	UBERON:0000451	46.69	gold quality
gastrocnemius	UBERON:0001388	46.33	gold quality
heart left ventricle	UBERON:0002084	46.14	gold quality
Ammon’s horn	UBERON:0001954	44.46	gold quality
anterior cingulate cortex	UBERON:0009835	43.92	gold quality
omental fat pad	UBERON:0010414	43.88	silver quality
tibial nerve	UBERON:0001323	43.83	gold quality
putamen	UBERON:0001874	43.67	silver quality
subcutaneous adipose tissue	UBERON:0002190	42.68	silver quality
right atrium auricular region	UBERON:0006631	42.57	silver quality
right coronary artery	UBERON:0001625	42.30	silver quality
skin of leg	UBERON:0001511	41.94	silver quality
lower esophagus muscularis layer	UBERON:0035833	41.68	silver quality
hypothalamus	UBERON:0001898	41.45	gold quality
caudate nucleus	UBERON:0001873	41.37	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.48

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.