LINC01770

Summary

LINC01770 (long intergenic non-protein coding RNA 1770, HGNC:52560) is a long non-coding RNA gene on chromosome 1p36.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52560
Approved symbol	LINC01770
Name	long intergenic non-protein coding RNA 1770
Location	1p36.33
Locus type	RNA, long non-coding
Status	Approved
Aliases	RRFERV
Ensembl gene	ENSG00000225285
Ensembl biotype	lncRNA
Entrez	102724312
RNAcentral	URS00007E413A — lncRNA, 1194 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 43 — 43 lncRNA

ENST00000417917, ENST00000430109, ENST00000434150, ENST00000454562, ENST00000729980, ENST00000729981, ENST00000729982, ENST00000729983, ENST00000729984, ENST00000729985, ENST00000729986, ENST00000729987, ENST00000729988, ENST00000729989, ENST00000729990, ENST00000729991, ENST00000729992, ENST00000729993, ENST00000729994, ENST00000729995, ENST00000729996, ENST00000729997, ENST00000729998, ENST00000729999, ENST00000730000, ENST00000730001, ENST00000730002, ENST00000730003, ENST00000730004, ENST00000730005, ENST00000730006, ENST00000730007, ENST00000730008, ENST00000730009, ENST00000730010, ENST00000730011, ENST00000730012, ENST00000730013, ENST00000730014, ENST00000730015, ENST00000730016, ENST00000730017, ENST00000730018

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000417917 — 3 exons

Exon	Start	End
ENSE00004058122	1429195	1430954
ENSE00004058133	1434178	1434584
ENSE00004058191	1435482	1435615

Expression profiles

Bgee: expression breadth ubiquitous, 170 present calls, max score 86.59.

Top tissues by expression

237 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.59	gold quality
lower esophagus muscularis layer	UBERON:0035833	86.30	gold quality
lower esophagus	UBERON:0013473	86.26	gold quality
muscle layer of sigmoid colon	UBERON:0035805	85.91	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	84.62	gold quality
buccal mucosa cell	CL:0002336	84.54	gold quality
pancreatic ductal cell	CL:0002079	83.94	silver quality
left uterine tube	UBERON:0001303	83.85	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	83.09	gold quality
mucosa of stomach	UBERON:0001199	82.71	gold quality
right uterine tube	UBERON:0001302	82.27	gold quality
tibial nerve	UBERON:0001323	79.83	gold quality
body of uterus	UBERON:0009853	79.79	gold quality
sural nerve	UBERON:0015488	79.55	gold quality
esophagus	UBERON:0001043	79.33	gold quality
prostate gland	UBERON:0002367	79.31	gold quality
minor salivary gland	UBERON:0001830	78.74	gold quality
right lobe of liver	UBERON:0001114	77.80	gold quality
saliva-secreting gland	UBERON:0001044	77.70	gold quality
mouth mucosa	UBERON:0003729	76.20	gold quality
endocervix	UBERON:0000458	75.85	gold quality
fallopian tube	UBERON:0003889	75.80	gold quality
body of stomach	UBERON:0001161	75.77	gold quality
ectocervix	UBERON:0012249	75.14	gold quality
fundus of stomach	UBERON:0001160	74.47	gold quality
colon	UBERON:0001155	74.06	gold quality
esophagus mucosa	UBERON:0002469	73.67	gold quality
large intestine	UBERON:0000059	73.36	gold quality
stomach	UBERON:0000945	73.07	gold quality
oviduct epithelium	UBERON:0004804	72.72	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.11

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.