LINC01776

Summary

LINC01776 (long intergenic non-protein coding RNA 1776, HGNC:52566) is a long non-coding RNA gene on chromosome 1p21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52566
Approved symbol	LINC01776
Name	long intergenic non-protein coding RNA 1776
Location	1p21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226053
Ensembl biotype	lncRNA
Entrez	729987
RNAcentral	URS0000759A4B — lncRNA, 2265 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000418344, ENST00000776603

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000418344 — 3 exons

Exon	Start	End
ENSE00001599497	98270595	98272658
ENSE00001661995	98249446	98249546
ENSE00001710049	98210747	98210810

Expression profiles

Bgee: expression breadth broad, 87 present calls, max score 78.58.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1786 / max 34.3514, expressed in 72 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
4156	0.1786	72

Top tissues by expression

87 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.58	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.22	gold quality
ventricular zone	UBERON:0003053	58.32	silver quality
cortical plate	UBERON:0005343	58.04	silver quality
ganglionic eminence	UBERON:0004023	58.01	gold quality
endometrium	UBERON:0001295	53.63	silver quality
calcaneal tendon	UBERON:0003701	52.08	silver quality
corpus callosum	UBERON:0002336	51.70	gold quality
blood	UBERON:0000178	51.35	silver quality
prefrontal cortex	UBERON:0000451	51.17	silver quality
lymph node	UBERON:0000029	50.39	silver quality
kidney	UBERON:0002113	49.79	silver quality
duodenum	UBERON:0002114	48.84	gold quality
left ovary	UBERON:0002119	47.90	gold quality
islet of Langerhans	UBERON:0000006	47.84	silver quality
urinary bladder	UBERON:0001255	47.47	silver quality
placenta	UBERON:0001987	47.34	gold quality
ovary	UBERON:0000992	46.84	gold quality
adenohypophysis	UBERON:0002196	46.35	gold quality
gall bladder	UBERON:0002110	46.16	silver quality
liver	UBERON:0002107	46.14	silver quality
adult mammalian kidney	UBERON:0000082	46.02	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	45.70	silver quality
adrenal gland	UBERON:0002369	45.48	silver quality
muscle of leg	UBERON:0001383	45.33	silver quality
heart left ventricle	UBERON:0002084	45.10	silver quality
pancreas	UBERON:0001264	44.54	silver quality
pituitary gland	UBERON:0000007	44.52	gold quality
heart	UBERON:0000948	44.41	silver quality
gastrocnemius	UBERON:0001388	44.21	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.12

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.