LINC01789

Summary

LINC01789 (long intergenic non-protein coding RNA 1789, HGNC:52578) is a long non-coding RNA gene on chromosome 2q12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52578
Approved symbol	LINC01789
Name	long intergenic non-protein coding RNA 1789
Location	2q12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229457
Ensembl biotype	lncRNA
Entrez	105373536
RNAcentral	URS00023443D2 — lncRNA, 560 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000443123, ENST00000455614

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000443123 — 4 exons

Exon	Start	End
ENSE00001634405	107266609	107266708
ENSE00001648376	107365480	107365873
ENSE00001704979	107264728	107264902
ENSE00001721987	107254691	107254881

Expression profiles

Bgee: expression breadth broad, 76 present calls, max score 72.62.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0286 / max 39.5494, expressed in 4 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
30071	0.0286	4

Top tissues by expression

76 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right lobe of thyroid gland	UBERON:0001119	72.62	gold quality
thyroid gland	UBERON:0002046	70.95	gold quality
left lobe of thyroid gland	UBERON:0001120	68.77	gold quality
cortex of kidney	UBERON:0001225	61.72	gold quality
lymph node	UBERON:0000029	54.14	gold quality
kidney	UBERON:0002113	54.04	gold quality
monocyte	CL:0000576	53.37	silver quality
multicellular organism	UBERON:0000468	53.25	gold quality
adult mammalian kidney	UBERON:0000082	51.50	gold quality
blood	UBERON:0000178	50.53	silver quality
prefrontal cortex	UBERON:0000451	49.59	gold quality
islet of Langerhans	UBERON:0000006	49.14	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	48.48	gold quality
bone marrow	UBERON:0002371	48.38	silver quality
putamen	UBERON:0001874	47.23	gold quality
placenta	UBERON:0001987	46.62	gold quality
gall bladder	UBERON:0002110	46.54	gold quality
body of pancreas	UBERON:0001150	46.38	silver quality
superior frontal gyrus	UBERON:0002661	46.34	silver quality
muscle of leg	UBERON:0001383	46.17	gold quality
frontal cortex	UBERON:0001870	45.36	gold quality
gastrocnemius	UBERON:0001388	45.09	silver quality
thoracic mammary gland	UBERON:0005200	44.54	silver quality
heart left ventricle	UBERON:0002084	43.93	silver quality
right lobe of liver	UBERON:0001114	43.85	silver quality
heart	UBERON:0000948	43.51	silver quality
tibial artery	UBERON:0007610	43.44	silver quality
cerebellar hemisphere	UBERON:0002245	43.13	silver quality
thoracic aorta	UBERON:0001515	43.09	silver quality
right frontal lobe	UBERON:0002810	42.68	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.42

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.