LINC01816

Summary

LINC01816 (long intergenic non-protein coding RNA 1816, HGNC:52621) is a long non-coding RNA gene on chromosome 2p13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52621
Approved symbol	LINC01816
Name	long intergenic non-protein coding RNA 1816
Location	2p13.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	LOC100133985
Ensembl gene	ENSG00000231327
Ensembl biotype	lncRNA
Entrez	100133985
RNAcentral	URS000075D7F0 — lncRNA, 661 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 17 — 17 lncRNA

ENST00000414141, ENST00000691543, ENST00000716052, ENST00000716053, ENST00000716054, ENST00000716055, ENST00000716056, ENST00000716057, ENST00000716058, ENST00000716059, ENST00000716060, ENST00000716061, ENST00000716062, ENST00000716063, ENST00000716064, ENST00000716065, ENST00000716066

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000414141 — 2 exons

Exon	Start	End
ENSE00004028698	70125046	70125346
ENSE00004028730	70124034	70124425

Expression profiles

Bgee: expression breadth ubiquitous, 156 present calls, max score 89.58.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 2.2598 / max 31.7484, expressed in 917 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
28998	2.2598	917

Top tissues by expression

242 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	89.58	gold quality
right lobe of liver	UBERON:0001114	72.48	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	70.86	gold quality
right adrenal gland	UBERON:0001233	70.49	gold quality
right adrenal gland cortex	UBERON:0035827	69.45	gold quality
ventricular zone	UBERON:0003053	68.42	gold quality
spinal cord	UBERON:0002240	68.23	gold quality
left adrenal gland	UBERON:0001234	68.22	gold quality
left adrenal gland cortex	UBERON:0035825	67.45	gold quality
putamen	UBERON:0001874	67.17	gold quality
nucleus accumbens	UBERON:0001882	67.15	gold quality
colonic epithelium	UBERON:0000397	67.02	silver quality
prefrontal cortex	UBERON:0000451	66.63	gold quality
ganglionic eminence	UBERON:0004023	66.31	gold quality
bone marrow cell	CL:0002092	66.29	silver quality
anterior cingulate cortex	UBERON:0009835	66.03	gold quality
adrenal cortex	UBERON:0001235	65.95	gold quality
adrenal gland	UBERON:0002369	65.90	gold quality
amygdala	UBERON:0001876	65.72	gold quality
caudate nucleus	UBERON:0001873	65.47	gold quality
apex of heart	UBERON:0002098	65.27	gold quality
hypothalamus	UBERON:0001898	65.19	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.17	gold quality
substantia nigra	UBERON:0002038	64.78	gold quality
epithelium of nasopharynx	UBERON:0001951	64.23	gold quality
adult mammalian kidney	UBERON:0000082	63.79	gold quality
granulocyte	CL:0000094	63.64	gold quality
right atrium auricular region	UBERON:0006631	63.60	gold quality
cortical plate	UBERON:0005343	63.50	gold quality
heart left ventricle	UBERON:0002084	63.39	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.57

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC01816 promotes the migration, invasion and epithelialmesenchymal transition of thyroid carcinoma cells by sponging miR34c5p and regulating CRABP2 expression levels. (PMID:33786631)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.