LINC01821

Summary

LINC01821 (long intergenic non-protein coding RNA 1821, HGNC:52626) is a long non-coding RNA gene on chromosome 2q32.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52626
Approved symbol	LINC01821
Name	long intergenic non-protein coding RNA 1821
Location	2q32.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225539
Ensembl biotype	lncRNA
Entrez	101927406
RNAcentral	URS000075A13C — lncRNA, 1083 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 65 — 65 lncRNA

ENST00000419786, ENST00000438505, ENST00000450848, ENST00000650872, ENST00000653542, ENST00000653550, ENST00000654688, ENST00000655549, ENST00000656546, ENST00000659259, ENST00000659759, ENST00000660800, ENST00000661930, ENST00000668090, ENST00000689500, ENST00000692688, ENST00000701609, ENST00000778639, ENST00000778640, ENST00000778641, ENST00000778642, ENST00000778643, ENST00000778644, ENST00000778645, ENST00000778646, ENST00000778647, ENST00000778648, ENST00000778649, ENST00000778650, ENST00000778651, ENST00000778652, ENST00000778653, ENST00000778654, ENST00000778655, ENST00000778656, ENST00000778657, ENST00000778658, ENST00000778659, ENST00000778660, ENST00000778661, ENST00000778662, ENST00000778663, ENST00000778664, ENST00000778665, ENST00000778666, ENST00000778667, ENST00000778668, ENST00000778669, ENST00000778670, ENST00000778671, ENST00000778672, ENST00000778673, ENST00000778674, ENST00000778675, ENST00000778676, ENST00000778677, ENST00000778678, ENST00000778679, ENST00000778680, ENST00000778681, ENST00000778682, ENST00000778683, ENST00000778684, ENST00000778685, ENST00000778686

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000419786 — 7 exons

Exon	Start	End
ENSE00001610978	194368841	194369072
ENSE00001651903	194374136	194374262
ENSE00001654359	194377212	194377337
ENSE00001695039	194416196	194416418
ENSE00001739480	194419308	194419645
ENSE00003856287	194344190	194344319
ENSE00003878265	194365413	194365555

Expression profiles

Bgee: expression breadth broad, 82 present calls, max score 84.03.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0335 / max 14.3536, expressed in 16 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
24411	0.0335	16

Top tissues by expression

187 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.03	gold quality
buccal mucosa cell	CL:0002336	68.83	silver quality
cortical plate	UBERON:0005343	67.38	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	64.51	gold quality
prefrontal cortex	UBERON:0000451	63.70	gold quality
anterior cingulate cortex	UBERON:0009835	62.56	gold quality
Brodmann (1909) area 9	UBERON:0013540	61.71	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	60.14	gold quality
amygdala	UBERON:0001876	59.61	gold quality
right frontal lobe	UBERON:0002810	59.44	gold quality
neocortex	UBERON:0001950	59.07	gold quality
testis	UBERON:0000473	58.71	gold quality
frontal cortex	UBERON:0001870	58.62	gold quality
leukocyte	CL:0000738	56.85	gold quality
monocyte	CL:0000576	56.73	gold quality
cerebral cortex	UBERON:0000956	56.51	gold quality
gall bladder	UBERON:0002110	55.60	gold quality
cartilage tissue	UBERON:0002418	53.72	gold quality
sperm	CL:0000019	53.59	gold quality
forebrain	UBERON:0001890	53.34	gold quality
temporal lobe	UBERON:0001871	52.98	gold quality
vena cava	UBERON:0004087	52.63	gold quality
brain	UBERON:0000955	52.53	gold quality
Brodmann (1909) area 46	UBERON:0006483	52.27	gold quality
right lobe of liver	UBERON:0001114	51.93	gold quality
right hemisphere of cerebellum	UBERON:0014890	50.90	gold quality
primary visual cortex	UBERON:0002436	50.52	silver quality
middle temporal gyrus	UBERON:0002771	50.23	gold quality
vermiform appendix	UBERON:0001154	49.96	gold quality
skin of hip	UBERON:0001554	49.11	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.41

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.