LINC01833

Summary

LINC01833 (long intergenic non-protein coding RNA 1833, HGNC:52644) is a long non-coding RNA gene on chromosome 2p21.

Predicted to be involved in regulation of gene expression.

Source: NCBI Gene 107985879 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52644
Approved symbol	LINC01833
Name	long intergenic non-protein coding RNA 1833
Location	2p21
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-89-K21.1
Ensembl gene	ENSG00000259439
Ensembl biotype	lncRNA
Entrez	107985879
RNAcentral	URS0000BC451C — lncRNA, 599 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 29 — 29 lncRNA

ENST00000430847, ENST00000432125, ENST00000437916, ENST00000444871, ENST00000560399, ENST00000685287, ENST00000760488, ENST00000760489, ENST00000760490, ENST00000760491, ENST00000760492, ENST00000760493, ENST00000760494, ENST00000760495, ENST00000760496, ENST00000760497, ENST00000760498, ENST00000760499, ENST00000760500, ENST00000760501, ENST00000760502, ENST00000760503, ENST00000760504, ENST00000760505, ENST00000760506, ENST00000760507, ENST00000760508, ENST00000760509, ENST00000760510

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000430847 — 2 exons

Exon	Start	End
ENSE00004114124	44935280	44935996
ENSE00004114126	44929975	44930247

Expression profiles

Bgee: expression breadth ubiquitous, 107 present calls, max score 91.82.

FANTOM5 (CAGE): breadth broad, TPM avg 1.1437 / max 63.3172, expressed in 263 samples.

FANTOM5 promoters (9 alternative TSS)

Promoter ID	TPM avg	Samples expressed
28150	0.3739	165
28146	0.2562	125
28143	0.1689	75
28147	0.1480	101
28153	0.0750	40
28152	0.0510	19
28148	0.0400	19
28151	0.0166	7
28149	0.0140	6

Top tissues by expression

209 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cardiac muscle of right atrium	UBERON:0003379	91.82	gold quality
left ventricle myocardium	UBERON:0006566	91.32	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	90.73	gold quality
adenohypophysis	UBERON:0002196	90.04	gold quality
pigmented layer of retina	UBERON:0001782	89.28	gold quality
nucleus accumbens	UBERON:0001882	87.05	gold quality
pituitary gland	UBERON:0000007	85.95	gold quality
caudate nucleus	UBERON:0001873	83.11	gold quality
putamen	UBERON:0001874	82.06	gold quality
upper arm skin	UBERON:0004263	80.02	gold quality
nasal cavity epithelium	UBERON:0005384	79.58	gold quality
nasal cavity mucosa	UBERON:0001826	78.40	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.51	gold quality
myocardium	UBERON:0002349	76.23	gold quality
epithelial cell of pancreas	CL:0000083	74.16	gold quality
tibialis anterior	UBERON:0001385	73.98	silver quality
hypothalamus	UBERON:0001898	72.24	gold quality
amygdala	UBERON:0001876	71.48	gold quality
ileal mucosa	UBERON:0000331	71.34	silver quality
ventricular zone	UBERON:0003053	68.22	gold quality
Brodmann (1909) area 9	UBERON:0013540	67.44	gold quality
forebrain	UBERON:0001890	66.89	gold quality
parotid gland	UBERON:0001831	66.12	gold quality
brain	UBERON:0000955	65.29	gold quality
right frontal lobe	UBERON:0002810	64.64	gold quality
pancreatic ductal cell	CL:0002079	64.46	silver quality
superficial temporal artery	UBERON:0001614	63.99	gold quality
adult mammalian kidney	UBERON:0000082	63.53	gold quality
islet of Langerhans	UBERON:0000006	63.14	gold quality
buccal mucosa cell	CL:0002336	61.82	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• LncRNA RP11-89 facilitates tumorigenesis and ferroptosis resistance through PROM2-activated iron export by sponging miR-129-5p in bladder cancer. (PMID:34728613)
• Cancer-associated fibroblasts derived exosomal LINC01833 promotes the occurrence of non-small cell lung cancer through miR-335-5p -VAPA axis. (PMID:39152098)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.