LINC01871

Summary

LINC01871 (long intergenic non-protein coding RNA 1871, HGNC:52690) is a long non-coding RNA gene on chromosome 2p25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52690
Approved symbol	LINC01871
Name	long intergenic non-protein coding RNA 1871
Location	2p25.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235576
Ensembl biotype	lncRNA
Entrez	101929531
RNAcentral	URS00026A21CD — lncRNA, 281 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 16 lncRNA

ENST00000417930, ENST00000690040, ENST00000690653, ENST00000811668, ENST00000811669, ENST00000811670, ENST00000811671, ENST00000811672, ENST00000811673, ENST00000811674, ENST00000811675, ENST00000811676, ENST00000811677, ENST00000811678, ENST00000811679, ENST00000811680

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000417930 — 3 exons

Exon	Start	End
ENSE00003924608	7730236	7730334
ENSE00004209862	7730516	7730724
ENSE00004209867	7725748	7725853

Expression profiles

Bgee: expression breadth ubiquitous, 122 present calls, max score 96.77.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 2.2426 / max 315.0174, expressed in 128 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
18703	1.3579	103
18704	0.8847	82

Top tissues by expression

122 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
granulocyte	CL:0000094	96.77	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	94.85	gold quality
lymph node	UBERON:0000029	89.66	gold quality
colonic epithelium	UBERON:0000397	88.83	gold quality
blood	UBERON:0000178	86.16	gold quality
spleen	UBERON:0002106	86.12	gold quality
vermiform appendix	UBERON:0001154	84.12	gold quality
bone marrow cell	CL:0002092	83.65	gold quality
small intestine	UBERON:0002108	83.07	gold quality
small intestine Peyer’s patch	UBERON:0003454	82.64	gold quality
mucosa of transverse colon	UBERON:0004991	82.59	gold quality
rectum	UBERON:0001052	82.09	gold quality
duodenum	UBERON:0002114	81.82	gold quality
gall bladder	UBERON:0002110	81.71	gold quality
bone marrow	UBERON:0002371	77.81	gold quality
right lung	UBERON:0002167	77.64	gold quality
tonsil	UBERON:0002372	77.04	gold quality
upper lobe of left lung	UBERON:0008952	76.74	gold quality
lung	UBERON:0002048	76.64	gold quality
omental fat pad	UBERON:0010414	76.35	gold quality
leukocyte	CL:0000738	75.33	gold quality
liver	UBERON:0002107	75.00	gold quality
intestine	UBERON:0000160	74.83	gold quality
transverse colon	UBERON:0001157	74.50	gold quality
body of stomach	UBERON:0001161	74.28	gold quality
stomach	UBERON:0000945	73.63	gold quality
cortex of kidney	UBERON:0001225	73.58	gold quality
urinary bladder	UBERON:0001255	73.56	gold quality
lower esophagus mucosa	UBERON:0035834	73.49	gold quality
skeletal muscle tissue	UBERON:0001134	72.30	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	16.66

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LncRNA LINC01871 sponging miR-142-3p to modulate ZYG11B promotes the chemoresistance of colorectal cancer cells by inducing autophagy. (PMID:36847071)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.