LINC01874

Summary

LINC01874 (long intergenic non-protein coding RNA 1874, HGNC:52693) is a long non-coding RNA gene on chromosome 2p25.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52693
Approved symbol	LINC01874
Name	long intergenic non-protein coding RNA 1874
Location	2p25.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000223985
Ensembl biotype	lncRNA
Entrez	727944
RNAcentral	URS0000BC4503 — lncRNA, 530 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000427398, ENST00000656189, ENST00000825685, ENST00000825686, ENST00000825687, ENST00000830612

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000427398 — 2 exons

Exon	Start	End
ENSE00001701276	492521	492655
ENSE00001704068	490944	491318

Expression profiles

Bgee: expression breadth broad, 49 present calls, max score 90.68.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0249 / max 33.2423, expressed in 4 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
26635	0.0170	3
26633	0.0052	1
26634	0.0027	1

Top tissues by expression

180 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	90.68	gold quality
adult mammalian kidney	UBERON:0000082	84.09	gold quality
kidney epithelium	UBERON:0004819	78.83	gold quality
kidney	UBERON:0002113	76.49	gold quality
cortex of kidney	UBERON:0001225	70.38	gold quality
anterior cingulate cortex	UBERON:0009835	63.76	gold quality
metanephros cortex	UBERON:0010533	63.35	gold quality
tibialis anterior	UBERON:0001385	61.94	silver quality
monocyte	CL:0000576	56.65	gold quality
metanephros	UBERON:0000081	56.45	gold quality
sural nerve	UBERON:0015488	56.14	silver quality
right lobe of thyroid gland	UBERON:0001119	55.95	gold quality
islet of Langerhans	UBERON:0000006	54.79	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
pancreatic ductal cell	CL:0002079	54.24	silver quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
epithelial cell of pancreas	CL:0000083	53.95	gold quality
cartilage tissue	UBERON:0002418	53.79	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
gastrocnemius	UBERON:0001388	52.47	silver quality
cardiac atrium	UBERON:0002081	51.83	gold quality
deltoid	UBERON:0001476	51.04	gold quality
myocardium	UBERON:0002349	50.25	gold quality
right adrenal gland cortex	UBERON:0035827	50.24	gold quality
adult organism	UBERON:0007023	49.48	gold quality
ileal mucosa	UBERON:0000331	49.42	silver quality
cerebellar vermis	UBERON:0004720	48.32	gold quality
pancreas	UBERON:0001264	47.88	gold quality
quadriceps femoris	UBERON:0001377	47.46	gold quality
nasal cavity epithelium	UBERON:0005384	47.03	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	7.73

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.