LINC01877

Summary

LINC01877 (long intergenic non-protein coding RNA 1877, HGNC:52696) is a long non-coding RNA gene on chromosome 2q33.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52696
Approved symbol	LINC01877
Name	long intergenic non-protein coding RNA 1877
Location	2q33.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000238217
Ensembl biotype	lncRNA
Entrez	101927641
RNAcentral	URS000075AD2F — lncRNA, 2365 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 17 — 17 lncRNA

ENST00000419243, ENST00000427045, ENST00000439734, ENST00000453035, ENST00000655676, ENST00000656508, ENST00000657231, ENST00000657450, ENST00000663879, ENST00000664879, ENST00000669659, ENST00000761334, ENST00000761335, ENST00000761336, ENST00000761337, ENST00000761338, ENST00000761339

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000419243 — 5 exons

Exon	Start	End
ENSE00001630523	199629925	199630099
ENSE00001659183	199608068	199608127
ENSE00001685384	199630246	199630715
ENSE00001721027	199629064	199629146
ENSE00001804967	199624532	199624596

Expression profiles

Bgee: expression breadth ubiquitous, 145 present calls, max score 80.05.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4041 / max 217.0966, expressed in 61 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
24515	0.4041	61

Top tissues by expression

231 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
C1 segment of cervical spinal cord	UBERON:0006469	80.05	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.14	gold quality
spinal cord	UBERON:0002240	76.61	gold quality
corpus callosum	UBERON:0002336	73.72	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	69.82	silver quality
substantia nigra	UBERON:0002038	69.38	gold quality
midbrain	UBERON:0001891	66.35	gold quality
Brodmann (1909) area 9	UBERON:0013540	66.30	gold quality
prefrontal cortex	UBERON:0000451	64.58	gold quality
hypothalamus	UBERON:0001898	63.32	gold quality
amygdala	UBERON:0001876	63.19	gold quality
sural nerve	UBERON:0015488	63.18	gold quality
putamen	UBERON:0001874	62.87	gold quality
right frontal lobe	UBERON:0002810	62.21	gold quality
anterior cingulate cortex	UBERON:0009835	62.14	gold quality
ganglionic eminence	UBERON:0004023	62.12	gold quality
calcaneal tendon	UBERON:0003701	61.60	gold quality
Ammon’s horn	UBERON:0001954	60.67	gold quality
caudate nucleus	UBERON:0001873	60.40	gold quality
nucleus accumbens	UBERON:0001882	60.39	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	60.17	gold quality
neocortex	UBERON:0001950	59.49	gold quality
frontal cortex	UBERON:0001870	59.13	gold quality
cerebral cortex	UBERON:0000956	58.21	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.03	silver quality
forebrain	UBERON:0001890	57.73	gold quality
brain	UBERON:0000955	57.20	gold quality
monocyte	CL:0000576	56.61	gold quality
adrenal tissue	UBERON:0018303	56.02	gold quality
primary visual cortex	UBERON:0002436	54.87	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.92

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.