LINC01915

Summary

LINC01915 (long intergenic non-protein coding RNA 1915, HGNC:52734) is a long non-coding RNA gene on chromosome 18q11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52734
Approved symbol	LINC01915
Name	long intergenic non-protein coding RNA 1915
Location	18q11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000265485
Ensembl biotype	lncRNA
Entrez	729950
RNAcentral	URS000050119D — lncRNA, 2321 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 35 — 35 lncRNA

ENST00000577994, ENST00000578490, ENST00000583558, ENST00000648293, ENST00000652945, ENST00000653857, ENST00000659746, ENST00000661107, ENST00000663563, ENST00000663756, ENST00000663865, ENST00000664008, ENST00000664770, ENST00000665252, ENST00000667449, ENST00000669467, ENST00000669666, ENST00000693529, ENST00000762860, ENST00000762862, ENST00000762863, ENST00000762864, ENST00000762865, ENST00000762866, ENST00000762867, ENST00000762868, ENST00000762869, ENST00000762870, ENST00000762871, ENST00000762872, ENST00000762873, ENST00000762874, ENST00000762875, ENST00000762876, ENST00000762877

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000577994 — 3 exons

Exon	Start	End
ENSE00002689902	24628182	24628263
ENSE00002723021	24660320	24662198
ENSE00002734942	24659735	24660094

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 74.88.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.8389 / max 554.9031, expressed in 73 samples.

FANTOM5 promoters (9 alternative TSS)

Promoter ID	TPM avg	Samples expressed
169747	0.5561	55
169748	0.2084	13
169751	0.0200	4
169750	0.0131	7
169755	0.0119	3
169752	0.0105	3
169753	0.0105	3
169754	0.0065	2
169756	0.0018	1

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.88	gold quality
calcaneal tendon	UBERON:0003701	72.92	gold quality
colonic epithelium	UBERON:0000397	72.33	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	68.61	gold quality
rectum	UBERON:0001052	66.12	gold quality
duodenum	UBERON:0002114	63.56	gold quality
cerebellar hemisphere	UBERON:0002245	63.22	gold quality
cerebellum	UBERON:0002037	63.19	gold quality
cerebellar cortex	UBERON:0002129	63.17	gold quality
endometrium	UBERON:0001295	62.73	gold quality
right hemisphere of cerebellum	UBERON:0014890	62.63	gold quality
spleen	UBERON:0002106	62.60	gold quality
sural nerve	UBERON:0015488	62.39	silver quality
heart left ventricle	UBERON:0002084	61.97	gold quality
mucosa of transverse colon	UBERON:0004991	61.53	gold quality
apex of heart	UBERON:0002098	60.94	gold quality
heart	UBERON:0000948	59.83	gold quality
right atrium auricular region	UBERON:0006631	58.75	gold quality
gall bladder	UBERON:0002110	57.80	gold quality
skeletal muscle tissue	UBERON:0001134	56.44	gold quality
muscle tissue	UBERON:0002385	56.33	gold quality
hindlimb stylopod muscle	UBERON:0004252	55.10	gold quality
transverse colon	UBERON:0001157	55.08	gold quality
small intestine	UBERON:0002108	54.52	gold quality
subcutaneous adipose tissue	UBERON:0002190	54.44	gold quality
prefrontal cortex	UBERON:0000451	54.33	gold quality
islet of Langerhans	UBERON:0000006	53.68	gold quality
superior frontal gyrus	UBERON:0002661	53.41	gold quality
intestine	UBERON:0000160	53.12	gold quality
monocyte	CL:0000576	53.09	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.84

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC01915 Facilitates the Conversion of Normal Fibroblasts into Cancer-Associated Fibroblasts Induced by Colorectal Cancer-Derived Extracellular Vesicles through the miR-92a-3p/KLF4/CH25H Axis. (PMID:34643375)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.