LINC01939

Summary

LINC01939 (long intergenic non-protein coding RNA 1939, HGNC:52762) is a long non-coding RNA gene on chromosome 2p25.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52762
Approved symbol	LINC01939
Name	long intergenic non-protein coding RNA 1939
Location	2p25.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228799
Ensembl biotype	lncRNA
Entrez	101060385
RNAcentral	URS00002E14A7 — lncRNA, 694 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000445279, ENST00000449405

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000445279 — 4 exons

Exon	Start	End
ENSE00001607211	901562	901718
ENSE00001727388	899462	900452
ENSE00001731950	901892	901959
ENSE00001748886	905220	905539

Expression profiles

Bgee: expression breadth broad, 85 present calls, max score 82.17.

Top tissues by expression

85 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.17	gold quality
right testis	UBERON:0004534	73.83	gold quality
left testis	UBERON:0004533	71.97	gold quality
testis	UBERON:0000473	71.91	gold quality
sural nerve	UBERON:0015488	63.80	silver quality
ganglionic eminence	UBERON:0004023	61.71	gold quality
hindlimb stylopod muscle	UBERON:0004252	61.48	gold quality
liver	UBERON:0002107	59.69	gold quality
skeletal muscle tissue	UBERON:0001134	57.01	silver quality
pituitary gland	UBERON:0000007	56.41	gold quality
cortex of kidney	UBERON:0001225	55.48	gold quality
monocyte	CL:0000576	54.74	silver quality
adenohypophysis	UBERON:0002196	53.89	gold quality
stromal cell of endometrium	CL:0002255	53.78	silver quality
lymph node	UBERON:0000029	53.09	gold quality
primary visual cortex	UBERON:0002436	50.90	gold quality
islet of Langerhans	UBERON:0000006	50.55	gold quality
multicellular organism	UBERON:0000468	50.21	gold quality
prefrontal cortex	UBERON:0000451	49.97	silver quality
blood	UBERON:0000178	49.59	silver quality
cerebellar cortex	UBERON:0002129	49.53	silver quality
cerebellar hemisphere	UBERON:0002245	49.46	silver quality
placenta	UBERON:0001987	49.31	silver quality
muscle of leg	UBERON:0001383	49.05	gold quality
endometrium	UBERON:0001295	48.92	silver quality
superior frontal gyrus	UBERON:0002661	48.81	gold quality
pancreas	UBERON:0001264	48.76	gold quality
right hemisphere of cerebellum	UBERON:0014890	48.05	gold quality
right lobe of thyroid gland	UBERON:0001119	48.01	gold quality
gastrocnemius	UBERON:0001388	47.46	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.96

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 3)

• our data suggest that the newly identified lncRNA LINC01939 might act as a potential prognostic biomarker for gastric cancer (PMID:30017335)
• LINC01939 expression was significantly decreased in gastric cancer tissues and cell lines and predicted adverse outcomes for gastric cancer patients. LINC01939 suppresses gastric cancer metastasis and EMT process via upregulating EGR2 expression. (PMID:30683847)
• Long intergenic non-coding RNA 1939 eliminates proliferation and migration of human renal cell carcinoma (RCC) cells by down-regulation of miR-154. (PMID:32138544)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.