LINC01945

Summary

LINC01945 (long intergenic non-protein coding RNA 1945, HGNC:52769) is a long non-coding RNA gene on chromosome 2q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52769
Approved symbol	LINC01945
Name	long intergenic non-protein coding RNA 1945
Location	2q21.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236485
Ensembl biotype	lncRNA
Entrez	101928067
RNAcentral	URS0000BC43AA — lncRNA, 1298 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 22 — 22 lncRNA

ENST00000419784, ENST00000729831, ENST00000729832, ENST00000729833, ENST00000729834, ENST00000729835, ENST00000729836, ENST00000729837, ENST00000729838, ENST00000729839, ENST00000729840, ENST00000729841, ENST00000729842, ENST00000729843, ENST00000729844, ENST00000729845, ENST00000729846, ENST00000729847, ENST00000729848, ENST00000729849, ENST00000729850, ENST00000729851

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000419784 — 7 exons

Exon	Start	End
ENSE00004057795	131993729	131994580
ENSE00004057815	132037309	132037475
ENSE00004057816	131997515	131997563
ENSE00004057822	132004111	132004233
ENSE00004057829	132037788	132038022
ENSE00004057836	131994941	131994987
ENSE00004057842	131983937	131984343

Expression profiles

Bgee: expression breadth broad, 55 present calls, max score 83.91.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0210 / max 3.7772, expressed in 7 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
30638	0.0210	7

Top tissues by expression

55 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.91	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.02	gold quality
liver	UBERON:0002107	71.97	gold quality
ventricular zone	UBERON:0003053	65.42	gold quality
nucleus accumbens	UBERON:0001882	61.38	gold quality
fundus of stomach	UBERON:0001160	58.35	gold quality
superior frontal gyrus	UBERON:0002661	56.93	gold quality
putamen	UBERON:0001874	54.73	gold quality
caudate nucleus	UBERON:0001873	54.45	gold quality
prefrontal cortex	UBERON:0000451	54.15	gold quality
Brodmann (1909) area 9	UBERON:0013540	53.03	gold quality
lymph node	UBERON:0000029	52.70	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	52.49	gold quality
brain	UBERON:0000955	52.32	gold quality
blood	UBERON:0000178	52.24	silver quality
frontal cortex	UBERON:0001870	52.23	gold quality
cerebral cortex	UBERON:0000956	51.72	gold quality
duodenum	UBERON:0002114	51.43	gold quality
anterior cingulate cortex	UBERON:0009835	51.15	gold quality
multicellular organism	UBERON:0000468	51.11	gold quality
right frontal lobe	UBERON:0002810	50.47	gold quality
tibial nerve	UBERON:0001323	49.78	gold quality
endometrium	UBERON:0001295	49.74	gold quality
Ammon’s horn	UBERON:0001954	49.40	gold quality
subcutaneous adipose tissue	UBERON:0002190	49.36	gold quality
body of stomach	UBERON:0001161	48.06	gold quality
transverse colon	UBERON:0001157	48.04	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	47.66	gold quality
muscle of leg	UBERON:0001383	46.73	silver quality
hypothalamus	UBERON:0001898	46.65	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.