LINC01946

Summary

LINC01946 (long intergenic non-protein coding RNA 1946, HGNC:52770) is a long non-coding RNA gene on chromosome 2p23.1-p22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52770
Approved symbol	LINC01946
Name	long intergenic non-protein coding RNA 1946
Location	2p23.1-p22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000223647
Ensembl biotype	lncRNA
Entrez	105374449
RNAcentral	URS0000BC4432 — lncRNA, 428 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000416279

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416279 — 5 exons

Exon	Start	End
ENSE00001637335	31794219	31794343
ENSE00001645469	31803958	31803980
ENSE00001706437	31793823	31793915
ENSE00001771109	31802947	31803115
ENSE00001791940	31794098	31794105

Expression profiles

Bgee: expression breadth broad, 91 present calls, max score 84.12.

Top tissues by expression

91 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.12	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.66	gold quality
bone marrow cell	CL:0002092	71.97	silver quality
bone marrow	UBERON:0002371	67.59	gold quality
islet of Langerhans	UBERON:0000006	60.87	gold quality
monocyte	CL:0000576	58.06	gold quality
cortex of kidney	UBERON:0001225	56.28	gold quality
blood	UBERON:0000178	56.04	gold quality
smooth muscle tissue	UBERON:0001135	55.73	gold quality
superior frontal gyrus	UBERON:0002661	55.62	gold quality
prefrontal cortex	UBERON:0000451	54.60	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	54.25	gold quality
adrenal tissue	UBERON:0018303	51.62	gold quality
muscle of leg	UBERON:0001383	51.26	gold quality
gastrocnemius	UBERON:0001388	51.21	gold quality
liver	UBERON:0002107	50.14	gold quality
urinary bladder	UBERON:0001255	49.23	gold quality
calcaneal tendon	UBERON:0003701	48.83	silver quality
kidney	UBERON:0002113	48.67	gold quality
fallopian tube	UBERON:0003889	47.51	gold quality
tibial artery	UBERON:0007610	47.29	gold quality
fundus of stomach	UBERON:0001160	47.00	gold quality
right lobe of liver	UBERON:0001114	46.97	silver quality
heart left ventricle	UBERON:0002084	46.74	gold quality
tonsil	UBERON:0002372	46.64	gold quality
right ovary	UBERON:0002118	46.45	gold quality
adrenal gland	UBERON:0002369	45.48	gold quality
left adrenal gland cortex	UBERON:0035825	45.21	gold quality
endocervix	UBERON:0000458	45.16	gold quality
multicellular organism	UBERON:0000468	45.08	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.96

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.