LINC01978
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Summary
LINC01978 (long intergenic non-protein coding RNA 1978, HGNC:52806) is a long non-coding RNA gene on chromosome 17q25.3.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:52806 |
| Approved symbol | LINC01978 |
| Name | long intergenic non-protein coding RNA 1978 |
| Location | 17q25.3 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000262188 |
| Ensembl biotype | lncRNA |
| Entrez | 101928738 |
| RNAcentral | URS00001648A8 — lncRNA, 1540 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 5 — 5 lncRNA
ENST00000572353, ENST00000574526, ENST00000655170, ENST00000771062, ENST00000771063
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000572353 — 2 exons
| Exon | Start | End |
|---|---|---|
| ENSE00002648316 | 79925126 | 79925462 |
| ENSE00002679135 | 79919374 | 79919576 |
Expression profiles
Bgee: expression breadth ubiquitous, 124 present calls, max score 76.35.
FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.5658 / max 54.0283, expressed in 144 samples.
FANTOM5 promoters (3 alternative TSS)
| Promoter ID | TPM avg | Samples expressed |
|---|---|---|
| 163193 | 0.4634 | 122 |
| 163194 | 0.0981 | 55 |
| 208434 | 0.0043 | 2 |
Top tissues by expression
124 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| C1 segment of cervical spinal cord | UBERON:0006469 | 76.35 | gold quality |
| lower esophagus mucosa | UBERON:0035834 | 71.35 | gold quality |
| substantia nigra | UBERON:0002038 | 70.61 | gold quality |
| duodenum | UBERON:0002114 | 69.88 | gold quality |
| Ammon’s horn | UBERON:0001954 | 67.45 | gold quality |
| corpus callosum | UBERON:0002336 | 67.27 | gold quality |
| putamen | UBERON:0001874 | 65.92 | gold quality |
| body of stomach | UBERON:0001161 | 64.79 | gold quality |
| primary visual cortex | UBERON:0002436 | 64.32 | gold quality |
| prefrontal cortex | UBERON:0000451 | 63.87 | gold quality |
| stomach | UBERON:0000945 | 63.73 | gold quality |
| Brodmann (1909) area 9 | UBERON:0013540 | 62.99 | gold quality |
| temporal lobe | UBERON:0001871 | 62.07 | gold quality |
| frontal cortex | UBERON:0001870 | 61.94 | gold quality |
| amygdala | UBERON:0001876 | 61.93 | gold quality |
| small intestine | UBERON:0002108 | 61.79 | gold quality |
| caudate nucleus | UBERON:0001873 | 61.33 | gold quality |
| small intestine Peyer’s patch | UBERON:0003454 | 61.13 | gold quality |
| gall bladder | UBERON:0002110 | 61.11 | gold quality |
| cerebral cortex | UBERON:0000956 | 60.78 | gold quality |
| cortical plate | UBERON:0005343 | 60.72 | gold quality |
| esophagus mucosa | UBERON:0002469 | 60.55 | gold quality |
| brain | UBERON:0000955 | 59.74 | gold quality |
| sural nerve | UBERON:0015488 | 59.40 | silver quality |
| right frontal lobe | UBERON:0002810 | 59.35 | gold quality |
| superior frontal gyrus | UBERON:0002661 | 59.06 | gold quality |
| ganglionic eminence | UBERON:0004023 | 58.98 | gold quality |
| hypothalamus | UBERON:0001898 | 58.81 | gold quality |
| fundus of stomach | UBERON:0001160 | 58.50 | gold quality |
| dorsolateral prefrontal cortex | UBERON:0009834 | 58.44 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 1.28 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): peroxisome biogenesis disorder 5A (Zellweger), peroxisome biogenesis disorder 5B