LINC01989

Summary

LINC01989 (long intergenic non-protein coding RNA 1989, HGNC:52821) is a long non-coding RNA gene on chromosome 17q12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52821
Approved symbol	LINC01989
Name	long intergenic non-protein coding RNA 1989
Location	17q12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261156
Ensembl biotype	lncRNA
Entrez	101927239
RNAcentral	URS0000759BFA — lncRNA, 1107 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000566930, ENST00000580792, ENST00000584724, ENST00000788268, ENST00000788269, ENST00000788270, ENST00000788271

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000566930 — 6 exons

Exon	Start	End
ENSE00002580720	34169372	34169559
ENSE00002585608	34174560	34174723
ENSE00002597991	34181966	34182098
ENSE00002607163	34179091	34179373
ENSE00002612747	34178713	34178973
ENSE00002719371	34183581	34183632

Expression profiles

Bgee: expression breadth broad, 87 present calls, max score 93.72.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0152 / max 15.3369, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
165282	0.0152	3

Top tissues by expression

87 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	93.72	gold quality
left testis	UBERON:0004533	85.77	gold quality
right testis	UBERON:0004534	85.52	gold quality
testis	UBERON:0000473	85.28	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	76.47	gold quality
stromal cell of endometrium	CL:0002255	73.09	gold quality
superior frontal gyrus	UBERON:0002661	66.84	gold quality
gall bladder	UBERON:0002110	65.60	gold quality
duodenum	UBERON:0002114	65.47	gold quality
Brodmann (1909) area 9	UBERON:0013540	64.92	gold quality
prefrontal cortex	UBERON:0000451	63.43	gold quality
monocyte	CL:0000576	63.18	gold quality
primary visual cortex	UBERON:0002436	62.60	gold quality
endometrium	UBERON:0001295	61.70	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	61.70	gold quality
frontal cortex	UBERON:0001870	60.77	gold quality
cerebral cortex	UBERON:0000956	60.46	gold quality
anterior cingulate cortex	UBERON:0009835	60.38	gold quality
islet of Langerhans	UBERON:0000006	60.19	gold quality
right frontal lobe	UBERON:0002810	60.14	gold quality
rectum	UBERON:0001052	59.73	gold quality
multicellular organism	UBERON:0000468	59.33	gold quality
nucleus accumbens	UBERON:0001882	58.33	gold quality
myometrium	UBERON:0001296	58.09	gold quality
muscle of leg	UBERON:0001383	57.63	gold quality
brain	UBERON:0000955	57.59	gold quality
gastrocnemius	UBERON:0001388	57.57	gold quality
Ammon’s horn	UBERON:0001954	56.57	gold quality
right lobe of liver	UBERON:0001114	56.12	gold quality
body of pancreas	UBERON:0001150	56.06	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.26

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.