LINC01991

Summary

LINC01991 (long intergenic non-protein coding RNA 1991, HGNC:52823) is a long non-coding RNA gene on chromosome 3q27.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52823
Approved symbol	LINC01991
Name	long intergenic non-protein coding RNA 1991
Location	3q27.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224187
Ensembl biotype	lncRNA
Entrez	105374266
RNAcentral	URS0000A76E0D — lncRNA, 752 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 14 — 14 lncRNA

ENST00000415940, ENST00000423643, ENST00000444379, ENST00000446091, ENST00000744770, ENST00000744771, ENST00000744772, ENST00000744773, ENST00000744774, ENST00000744775, ENST00000744776, ENST00000744777, ENST00000744778, ENST00000744779

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000415940 — 2 exons

Exon	Start	End
ENSE00001745998	187997422	187997758
ENSE00001775582	188003901	188003990

Expression profiles

Bgee: expression breadth broad, 77 present calls, max score 79.57.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0572 / max 44.0188, expressed in 6 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
46022	0.0279	5
46024	0.0152	4
46023	0.0141	4

Top tissues by expression

77 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
lymph node	UBERON:0000029	79.57	gold quality
tonsil	UBERON:0002372	78.29	gold quality
muscle tissue	UBERON:0002385	75.36	gold quality
metanephros cortex	UBERON:0010533	68.85	gold quality
cortex of kidney	UBERON:0001225	63.03	gold quality
vermiform appendix	UBERON:0001154	58.57	gold quality
liver	UBERON:0002107	57.80	gold quality
apex of heart	UBERON:0002098	57.16	gold quality
granulocyte	CL:0000094	55.78	gold quality
saliva-secreting gland	UBERON:0001044	52.41	gold quality
Brodmann (1909) area 9	UBERON:0013540	52.22	gold quality
blood	UBERON:0000178	51.72	gold quality
left ovary	UBERON:0002119	51.25	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	51.11	gold quality
muscle of leg	UBERON:0001383	51.00	gold quality
monocyte	CL:0000576	50.78	silver quality
adult mammalian kidney	UBERON:0000082	50.48	gold quality
prefrontal cortex	UBERON:0000451	50.35	gold quality
gastrocnemius	UBERON:0001388	50.35	gold quality
islet of Langerhans	UBERON:0000006	50.31	gold quality
colon	UBERON:0001155	49.08	gold quality
right lobe of liver	UBERON:0001114	47.63	silver quality
heart left ventricle	UBERON:0002084	47.59	gold quality
putamen	UBERON:0001874	47.21	gold quality
body of pancreas	UBERON:0001150	46.91	gold quality
multicellular organism	UBERON:0000468	46.75	gold quality
heart	UBERON:0000948	46.68	gold quality
urinary bladder	UBERON:0001255	46.65	silver quality
left adrenal gland cortex	UBERON:0035825	46.42	gold quality
Ammon’s horn	UBERON:0001954	46.27	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.62

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.