LINC01994

Summary

LINC01994 (long intergenic non-protein coding RNA 1994, HGNC:52827) is a long non-coding RNA gene on chromosome 3q26.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52827
Approved symbol	LINC01994
Name	long intergenic non-protein coding RNA 1994
Location	3q26.33
Locus type	RNA, long non-coding
Status	Approved
Aliases	CASCADES
Ensembl gene	ENSG00000241098
Ensembl biotype	lncRNA
Entrez	401103
RNAcentral	URS000075EB02 — lncRNA, 1806 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 24 — 24 lncRNA

ENST00000489016, ENST00000496220, ENST00000661576, ENST00000662733, ENST00000715738, ENST00000715740, ENST00000715741, ENST00000767325, ENST00000767326, ENST00000767327, ENST00000767328, ENST00000767329, ENST00000767330, ENST00000767331, ENST00000767332, ENST00000767333, ENST00000767334, ENST00000767336, ENST00000767339, ENST00000767341, ENST00000767343, ENST00000767344, ENST00000767345, ENST00000767346

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000489016 — 4 exons

Exon	Start	End
ENSE00001858883	182507083	182507124
ENSE00001889593	182504079	182504454
ENSE00001907428	182504672	182504714
ENSE00001953295	182498264	182498423

Expression profiles

Bgee: expression breadth broad, 23 present calls, max score 59.59.

Top tissues by expression

23 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
muscle tissue	UBERON:0002385	59.59	silver quality
ganglionic eminence	UBERON:0004023	57.05	silver quality
muscle of leg	UBERON:0001383	54.03	silver quality
urinary bladder	UBERON:0001255	51.16	silver quality
prefrontal cortex	UBERON:0000451	50.69	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	47.51	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	45.71	silver quality
hypothalamus	UBERON:0001898	44.87	silver quality
Brodmann (1909) area 9	UBERON:0013540	44.22	silver quality
anterior cingulate cortex	UBERON:0009835	44.19	silver quality
nucleus accumbens	UBERON:0001882	43.90	silver quality
saliva-secreting gland	UBERON:0001044	42.60	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	42.42	silver quality
putamen	UBERON:0001874	42.23	silver quality
substantia nigra	UBERON:0002038	41.45	silver quality
Ammon’s horn	UBERON:0001954	41.03	silver quality
zone of skin	UBERON:0000014	40.95	silver quality
minor salivary gland	UBERON:0001830	40.56	gold quality
esophagus mucosa	UBERON:0002469	40.29	silver quality
skin of abdomen	UBERON:0001416	39.69	silver quality
skin of leg	UBERON:0001511	39.62	silver quality
amygdala	UBERON:0001876	38.27	silver quality
tibial nerve	UBERON:0001323	35.89	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.