LINC02016

Summary

LINC02016 (long intergenic non-protein coding RNA 2016, HGNC:52851) is a long non-coding RNA gene on chromosome 3q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52851
Approved symbol	LINC02016
Name	long intergenic non-protein coding RNA 2016
Location	3q21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000244215
Ensembl biotype	lncRNA
Entrez	101927123
RNAcentral	URS000075CE52 — lncRNA, 948 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000488425, ENST00000654968, ENST00000662154, ENST00000663573, ENST00000829510

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000488425 — 5 exons

Exon	Start	End
ENSE00001823072	127322307	127322727
ENSE00001870016	127390446	127390670
ENSE00001877771	127355890	127355940
ENSE00001923195	127324535	127324731
ENSE00002420999	127356251	127356283

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 80.01.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0029 / max 3.2075, expressed in 2 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
44367	0.0029	2

Top tissues by expression

209 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.01	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.81	gold quality
cortical plate	UBERON:0005343	70.69	gold quality
ganglionic eminence	UBERON:0004023	68.81	gold quality
right lung	UBERON:0002167	63.93	gold quality
upper lobe of left lung	UBERON:0008952	62.30	gold quality
upper lobe of lung	UBERON:0008948	60.71	gold quality
prefrontal cortex	UBERON:0000451	58.81	gold quality
lung	UBERON:0002048	56.43	gold quality
monocyte	CL:0000576	55.36	gold quality
leukocyte	CL:0000738	55.15	silver quality
anterior cingulate cortex	UBERON:0009835	52.85	gold quality
frontal cortex	UBERON:0001870	52.70	gold quality
Brodmann (1909) area 9	UBERON:0013540	52.68	gold quality
neocortex	UBERON:0001950	52.45	gold quality
right frontal lobe	UBERON:0002810	52.41	gold quality
amygdala	UBERON:0001876	52.08	gold quality
sural nerve	UBERON:0015488	51.67	silver quality
right adrenal gland cortex	UBERON:0035827	51.35	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	50.84	gold quality
hypothalamus	UBERON:0001898	50.70	gold quality
ectocervix	UBERON:0012249	50.67	gold quality
cerebral cortex	UBERON:0000956	50.02	gold quality
islet of Langerhans	UBERON:0000006	49.71	gold quality
adrenal tissue	UBERON:0018303	49.17	silver quality
left adrenal gland cortex	UBERON:0035825	48.51	gold quality
right lobe of liver	UBERON:0001114	48.36	silver quality
Ammon’s horn	UBERON:0001954	48.01	gold quality
forebrain	UBERON:0001890	47.67	gold quality
adrenal cortex	UBERON:0001235	47.27	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.14

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.