LINC02038

Summary

LINC02038 (long intergenic non-protein coding RNA 2038, HGNC:52878) is a long non-coding RNA gene on chromosome 3q29.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52878
Approved symbol	LINC02038
Name	long intergenic non-protein coding RNA 2038
Location	3q29
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229155
Ensembl biotype	lncRNA
Entrez	105374285
RNAcentral	URS0000BC4453 — lncRNA, 2434 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000439074, ENST00000445168, ENST00000837985

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000439074 — 3 exons

Exon	Start	End
ENSE00001603151	193841868	193842755
ENSE00001745672	193843652	193844009
ENSE00001775230	193843078	193843225

Expression profiles

Bgee: expression breadth broad, 72 present calls, max score 83.44.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0727 / max 20.0389, expressed in 39 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
46179	0.0339	17
46177	0.0203	8
46178	0.0184	8

Top tissues by expression

72 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
gall bladder	UBERON:0002110	83.44	gold quality
rectum	UBERON:0001052	77.24	gold quality
duodenum	UBERON:0002114	73.87	gold quality
transverse colon	UBERON:0001157	67.53	gold quality
colon	UBERON:0001155	64.97	gold quality
colonic epithelium	UBERON:0000397	64.44	silver quality
stomach	UBERON:0000945	63.53	gold quality
body of stomach	UBERON:0001161	62.77	gold quality
metanephros cortex	UBERON:0010533	62.25	gold quality
intestine	UBERON:0000160	62.05	gold quality
mucosa of transverse colon	UBERON:0004991	61.93	gold quality
adult mammalian kidney	UBERON:0000082	61.84	gold quality
kidney	UBERON:0002113	61.69	gold quality
islet of Langerhans	UBERON:0000006	60.75	gold quality
lung	UBERON:0002048	60.01	gold quality
cortex of kidney	UBERON:0001225	59.16	gold quality
smooth muscle tissue	UBERON:0001135	58.92	gold quality
pancreas	UBERON:0001264	57.62	gold quality
urinary bladder	UBERON:0001255	57.46	gold quality
vermiform appendix	UBERON:0001154	56.47	gold quality
mucosa of stomach	UBERON:0001199	56.37	gold quality
multicellular organism	UBERON:0000468	56.03	gold quality
prefrontal cortex	UBERON:0000451	56.01	gold quality
body of pancreas	UBERON:0001150	55.54	gold quality
small intestine	UBERON:0002108	54.55	gold quality
liver	UBERON:0002107	54.22	gold quality
fundus of stomach	UBERON:0001160	53.88	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	53.04	gold quality
muscle layer of sigmoid colon	UBERON:0035805	52.73	gold quality
monocyte	CL:0000576	52.10	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.32

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• m[6]A-mediated LINC02038 inhibits colorectal cancer progression via regulation of the FAM172A/PI3K/AKT pathway via competitive binding with miR-552-5p. (PMID:37264959)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.