LINC02053

Summary

LINC02053 (long intergenic non-protein coding RNA 2053, HGNC:52893) is a long non-coding RNA gene on chromosome 3q26.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52893
Approved symbol	LINC02053
Name	long intergenic non-protein coding RNA 2053
Location	3q26.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000241696
Ensembl biotype	lncRNA
Entrez	100505609
RNAcentral	URS00008E3986 — lncRNA, 936 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 17 — 17 lncRNA

ENST00000464537, ENST00000488262, ENST00000653805, ENST00000654328, ENST00000668671, ENST00000670709, ENST00000670884, ENST00000831001, ENST00000831002, ENST00000831003, ENST00000831004, ENST00000831005, ENST00000831006, ENST00000831007, ENST00000831008, ENST00000831009, ENST00000831010

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000464537 — 2 exons

Exon	Start	End
ENSE00004246040	180422087	180422506
ENSE00004246042	180414173	180414396

Expression profiles

Bgee: expression breadth broad, 48 present calls, max score 94.01.

Top tissues by expression

164 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	94.01	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.16	gold quality
sperm	CL:0000019	83.21	gold quality
left testis	UBERON:0004533	73.67	gold quality
testis	UBERON:0000473	71.95	gold quality
right testis	UBERON:0004534	71.63	gold quality
sural nerve	UBERON:0015488	62.06	silver quality
upper leg skin	UBERON:0004262	59.94	gold quality
monocyte	CL:0000576	54.85	gold quality
endothelial cell	CL:0000115	52.66	gold quality
vermiform appendix	UBERON:0001154	51.73	gold quality
upper lobe of lung	UBERON:0008948	51.39	silver quality
lower lobe of lung	UBERON:0008949	51.11	silver quality
muscle layer of sigmoid colon	UBERON:0035805	49.51	gold quality
left lobe of thyroid gland	UBERON:0001120	48.77	gold quality
muscle of leg	UBERON:0001383	47.47	silver quality
islet of Langerhans	UBERON:0000006	47.38	silver quality
tibial nerve	UBERON:0001323	47.33	gold quality
gastrocnemius	UBERON:0001388	46.88	silver quality
calcaneal tendon	UBERON:0003701	46.62	silver quality
tibial artery	UBERON:0007610	45.99	silver quality
right frontal lobe	UBERON:0002810	45.37	gold quality
body of pancreas	UBERON:0001150	45.28	silver quality
anatomical system	UBERON:0000467	45.02	gold quality
skin of leg	UBERON:0001511	45.01	gold quality
material anatomical entity	UBERON:0000465	44.80	gold quality
multicellular organism	UBERON:0000468	44.71	gold quality
gall bladder	UBERON:0002110	44.64	silver quality
caecum	UBERON:0001153	44.09	gold quality
transverse colon	UBERON:0001157	43.58	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.79

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.