LINC02057

Summary

LINC02057 (long intergenic non-protein coding RNA 2057, HGNC:52900) is a long non-coding RNA gene on chromosome 5q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52900
Approved symbol	LINC02057
Name	long intergenic non-protein coding RNA 2057
Location	5q12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249279
Ensembl biotype	lncRNA
Entrez	105378992
RNAcentral	URS0000BC448C — lncRNA, 652 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 15 lncRNA

ENST00000503882, ENST00000511794, ENST00000659829, ENST00000661728, ENST00000820877, ENST00000820878, ENST00000820879, ENST00000820880, ENST00000820881, ENST00000820882, ENST00000820883, ENST00000820884, ENST00000820885, ENST00000820886, ENST00000820887

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000503882 — 3 exons

Exon	Start	End
ENSE00002024848	61250557	61250862
ENSE00002052549	61264777	61264929
ENSE00002057913	61252709	61252889

Expression profiles

Bgee: expression breadth ubiquitous, 116 present calls, max score 83.68.

FANTOM5 (CAGE): breadth broad, TPM avg 1.1182 / max 49.6897, expressed in 366 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
61909	0.7412	299
61908	0.2062	122
61907	0.1708	97

Top tissues by expression

116 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.68	gold quality
sural nerve	UBERON:0015488	79.25	gold quality
colonic epithelium	UBERON:0000397	78.44	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	71.49	gold quality
right uterine tube	UBERON:0001302	68.78	gold quality
ganglionic eminence	UBERON:0004023	66.47	gold quality
stromal cell of endometrium	CL:0002255	66.02	gold quality
cortical plate	UBERON:0005343	65.84	gold quality
skeletal muscle tissue	UBERON:0001134	65.29	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	63.30	silver quality
muscle tissue	UBERON:0002385	63.02	gold quality
rectum	UBERON:0001052	61.80	gold quality
transverse colon	UBERON:0001157	60.20	gold quality
fallopian tube	UBERON:0003889	60.01	gold quality
tonsil	UBERON:0002372	58.55	silver quality
saliva-secreting gland	UBERON:0001044	58.13	gold quality
minor salivary gland	UBERON:0001830	58.09	gold quality
bone marrow	UBERON:0002371	57.64	gold quality
mucosa of transverse colon	UBERON:0004991	57.13	gold quality
colon	UBERON:0001155	57.00	gold quality
urinary bladder	UBERON:0001255	56.48	gold quality
vagina	UBERON:0000996	56.44	gold quality
calcaneal tendon	UBERON:0003701	56.29	gold quality
monocyte	CL:0000576	54.97	gold quality
islet of Langerhans	UBERON:0000006	54.71	gold quality
right lung	UBERON:0002167	54.68	gold quality
intestine	UBERON:0000160	54.58	gold quality
placenta	UBERON:0001987	54.15	gold quality
endometrium	UBERON:0001295	53.95	gold quality
stomach	UBERON:0000945	53.58	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.21

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.