LINC02074

Summary

LINC02074 (long intergenic non-protein coding RNA 2074, HGNC:52920) is a long non-coding RNA gene on chromosome 17q25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52920
Approved symbol	LINC02074
Name	long intergenic non-protein coding RNA 2074
Location	17q25.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000266357
Ensembl biotype	lncRNA
Entrez	102723567
RNAcentral	URS00026A24E6 — lncRNA, 2815 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 33 — 33 lncRNA

ENST00000581028, ENST00000584003, ENST00000653467, ENST00000654301, ENST00000666198, ENST00000668167, ENST00000727554, ENST00000727555, ENST00000727556, ENST00000727557, ENST00000727558, ENST00000727559, ENST00000727560, ENST00000727561, ENST00000727562, ENST00000727563, ENST00000727564, ENST00000727565, ENST00000727566, ENST00000727567, ENST00000727568, ENST00000727569, ENST00000727570, ENST00000727571, ENST00000727572, ENST00000727573, ENST00000727574, ENST00000727575, ENST00000727576, ENST00000727577, ENST00000727578, ENST00000727579, ENST00000727580

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000581028 — 4 exons

Exon	Start	End
ENSE00002693776	74112646	74112899
ENSE00002718369	74106880	74106981
ENSE00002721085	74091022	74091176
ENSE00002728601	74043452	74043509

Expression profiles

Bgee: expression breadth broad, 92 present calls, max score 83.60.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0694 / max 15.7880, expressed in 21 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
167922	0.0694	21

Top tissues by expression

92 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.60	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	77.82	gold quality
testis	UBERON:0000473	63.88	gold quality
calcaneal tendon	UBERON:0003701	62.80	gold quality
right testis	UBERON:0004534	62.58	gold quality
left testis	UBERON:0004533	62.38	gold quality
ventricular zone	UBERON:0003053	60.43	gold quality
superior frontal gyrus	UBERON:0002661	58.54	gold quality
ganglionic eminence	UBERON:0004023	56.89	silver quality
prefrontal cortex	UBERON:0000451	56.67	gold quality
hindlimb stylopod muscle	UBERON:0004252	55.40	gold quality
bone marrow	UBERON:0002371	55.07	silver quality
stromal cell of endometrium	CL:0002255	54.71	silver quality
urinary bladder	UBERON:0001255	54.22	gold quality
muscle of leg	UBERON:0001383	53.73	gold quality
blood	UBERON:0000178	52.65	gold quality
frontal cortex	UBERON:0001870	52.19	gold quality
monocyte	CL:0000576	51.36	silver quality
lymph node	UBERON:0000029	50.31	silver quality
Brodmann (1909) area 9	UBERON:0013540	50.28	gold quality
cerebral cortex	UBERON:0000956	50.18	gold quality
endometrium	UBERON:0001295	49.74	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	49.44	gold quality
multicellular organism	UBERON:0000468	49.20	gold quality
liver	UBERON:0002107	48.93	gold quality
islet of Langerhans	UBERON:0000006	48.74	gold quality
right ovary	UBERON:0002118	48.62	gold quality
anterior cingulate cortex	UBERON:0009835	48.48	gold quality
brain	UBERON:0000955	47.54	gold quality
right frontal lobe	UBERON:0002810	47.13	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.44

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.